Results 81 to 90 of about 3,890,023 (314)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Development of a WHO growth reference for school-aged children and adolescents

Bulletin of the World Health Organization, 2007
OBJECTIVE: To construct growth curves for school-aged children and adolescents that accord with the WHO Child Growth Standards for preschool children and the body mass index (BMI) cut-offs for adults.
Mercedes de Onis, Adelheid W Onyango, Elaine Borghi, Amani Siyam, Chizuru Nishida, Jonathan Siekmann   +5 more
doaj  

Providing universal access to antiretroviral therapy in Thyolo, Malawi through task shifting and decentralization of HIV/AIDS care. [PDF]

, 2010
Objective  To describe how district-wide access to HIV/AIDS care was achieved and maintained in Thyolo District, Malawi. Method  In mid-2003, the Ministry of Health and Médecins Sans Frontières developed a model of care for Thyolo district (population ...
Adam, Battegay, Braitstein, Callaghan, Ferradini, Harries, Hirschhorn, Libamba, Massaquoi, Miller, Ministry of Health, National Statistic Office, National Statistics Office, Nkandu, Philips, Torpey, Weidle, World Bank, World Health Organization, World Health Organization, Zachariah   +20 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Clinical Performance of an Automated Reader in Interpreting Malaria Rapid Diagnostic Tests in Tanzania. [PDF]

, 2013
Parasitological confirmation of malaria is now recommended in all febrile patients by the World Health Organization (WHO) to reduce inappropriate use of anti-malarial drugs.
Ali Mohammed, Caroline Mavere, D Bell, D Njama-Meya, D-S Lee, DN Durrheim, E Nicastri, G Mtove, J Kahama-Maro, KM Learmonth, Marcela Cancino, MI Masanja, ML McMorrow, ML McMorrow, Omar Juma, P Mukadi, P Mukadi, RE Coleman, SA Harvey, Salim Abdulla, Santiago Ferro, Seif Shekalaghe, SP Kachur, V D’Acremont, V D’Acremont, W Rennie, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, YA Afrane, YH Chiu   +32 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Migration of health-care workers from developing countries: strategic approaches to its management

Bulletin of the World Health Organization, 2004
Of the 175 million people (2.9% of the world's population) living outside their country of birth in 2000, 65 million were economically active. The rise in the number of people migrating is significant for many developing countries because they are losing
Barbara Stilwell, Khassoum Diallo, Pascal Zurn, Marko Vujicic, Orvill Adams, Mario Dal Poz   +5 more
doaj  

Reaching the global tuberculosis control targets in the Western Pacific Region

Bulletin of the World Health Organization
PROBLEM: In 1999, a tuberculosis (TB) crisis was declared in the Western Pacific Region. APPROACH: In response, WHO established the Stop TB Special Project, which sought to halve 2000 levels of TB prevalence and mortality by 2010 through first reaching ...
Pieter van Maaren, Bernard Tomas, Philippe Glaziou, Takeshi Kasai, Dongil Ahn   +4 more
doaj   +1 more source

World Health Organization [PDF]

Heart, 2000
M, Davies, A, Hollman
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source