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World Health Organization [PDF]

International Organization, 1954
The Executive Board of the World Health Organization held its 14th session i n Geneva on May 27 and 28, 1954. Dr. H. Hyde (United States) was elected Chairman of the Board. Many of the decisions taken by the Executive Board implemented recommendations approved at the seventh World Health Assembly..
openaire   +2 more sources

Global challenges and solutions to achieving and sustaining measles and rubella elimination

Revista Panamericana de Salud Pública
Measles and rubella have long been recognized as priorities for disease prevention because of their devastating consequences for child health; hence, all World Health Organization (WHO) regions currently have a goal to eliminate measles and four out of ...
Natasha S. Crowcroft, Anna A. Minta, Sebastien Antoni, Lee Lee Ho, William Perea, Mick N. Mulders, Anindya Sekhar Bose, Aaron Wallace, Diana Chang Blanc, Patrick M. O’Connor   +9 more
doaj   +1 more source

The role of supportive supervision using mobile technology in monitoring and guiding program performance: a case study in Nigeria, 2015–2016

BMC Public Health, 2018
Background Supportive supervision is one of the interventions that fosters program improvement by way of imparting knowledge and skills to health workers.
Sisay G. Tegegne, Faisal Shuaib, Fiona Braka, Pascal Mkanda, Tesfaye B. Erbeto, Aron Aregay, Oyaole D. Rasheed, Akpan G. Ubong, Njie Alpha, Ahmed Khedr, Mirghani A. Isameldin, Yared G. Yehushualet, Charity Warigon, Usman Adamu, Eunice Damisa, Bassey Okposen, Peter Nsubuga, Rui G. Vaz, Wondimagegnehu Alemu   +18 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

An evaluation of a global vitamin and mineral nutrition surveillance system

Archivos Latinoamericanos de Nutrición
Evaluation at all levels is a fundamental function at World Health Organization (WHO). Evaluation of public health surveillance systems is essential to ensure that problems of public health importance are monitored efficiently and effectively.
Nancy Jennings Aburto, Lisa Rogers, Luz Maria De-Regil, Vipat Kuruchittham, Grace Rob, Raheel Arif, Juan Pablo Peña-Rosas   +6 more
doaj  

Polio eradication in Nigeria: evaluation of the quality of acute flaccid paralysis surveillance documentation in Bauchi state, 2016

BMC Public Health, 2018
Background Nigeria is the only country in Africa that is yet to be certified as polio free. Surveillance for acute flaccid paralysis (AFP) is the foundation of the polio eradication initiative since it provides information to alert both health managers ...
Adamu Ibrahim Ningi, Faisal Shuaib, Luka Mangveep Ibrahim, Jalal-Eddeen Abubakar Saleh, Khalid Abdelrahim, Isah Mohammed Bello, Bashir Abba, Ticha Jonhson Muluh, Fiona Braka, Sisay G. Tegegne, Abdullahi Wallah, Charles Korir, Samuel Bawa, Mahmood Saidu, Peter Nsubuga   +14 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source