Results 41 to 50 of about 1,198,222 (315)

Assessment of unmet needs to address noncompliant households during polio supplemental immunization activities in Kaduna state, 2014–2016

BMC Public Health, 2018
Background Despite concerted global efforts being made to eradicate poliomyelitis, the wild poliovirus still circulates in three countries, including Nigeria.
Hadiza Aliyu Iyal, Faisal Shuaib, Madubu Dauda, Abdullahi Suleiman, Fiona Braka, Sisay G. Tegegne, Peter Nsubuga, Terna Nomhwange, Yared G. Yehualashet, Sambo Ishaku, Charity Warigon, Furera Zakari, Gregory Umeh, Lami Samaila, Basirat Abdullahi, Kulchumi Hammanyero, Paul Dogo, Dawud Adamu, Rui G. Vaz, Wondimagegnehu Alemu   +19 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Revitalization of integrated disease surveillance and response in Sierra Leone post Ebola virus disease outbreak

BMC Public Health, 2019
Background The Ministry of Health and Sanitation (MOHS) in Sierra Leone partially rolled out the implementation of Integrated Disease Surveillance and Response (IDSR) in 2003.
Charles Njuguna, Amara Jambai, Alexander Chimbaru, Anders Nordstrom, Roland Conteh, Anderson Latt, Shikanga O-tipo, Robert Musoke, Jane Githuku, Zablon Yoti, Ali Yahaya, Ambrose Talisuna, Soatiana Rajatonirina, Ibrahima Socé Fall   +13 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Global data on visual impairment in the year 2002

Bulletin of the World Health Organization, 2004
This paper presents estimates of the prevalence of visual impairment and its causes in 2002, based on the best available evidence derived from recent studies. Estimates were determined from data on low vision and blindness as defined in the International
Serge Resnikoff, Donatella Pascolini, Daniel Etya'ale, Ivo Kocur, Ramachandra Pararajasegaram, Gopal P. Pokharel, Silvio P. Mariotti   +6 more
doaj  

Can non-physician health-care workers assess and manage cardiovascular risk in primary care?

Bulletin of the World Health Organization
OBJECTIVE: To ascertain the reliability of applying the WHO Cardiovascular Risk Management Package by non-physician health-care workers (NPHWs) in typical primary health-care settings.
Dele O Abegunde, Bakuti Shengelia, Anne Luyten, Alexandra Cameron, Francesca Celletti, Sania Nishtar, Vasu Pandurangi, Shanthi Mendis   +7 more
doaj   +1 more source

World health: the magazine of the World Health Organization: July-August 1973 [full issue]

, 1973
[47] p.World Health's history goes back to 1948, when a simple information sheet reflecting the beginnings of the organization, the WHO Newsletter, was distributed to the press.
World Health Organization
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Tuberculosis—a World Health Organization Perspective

Microbiology Spectrum, 2017
ABSTRACT Tuberculosis (TB) is an important cause of morbidity and mortality worldwide. The World Health Organization (WHO) has implemented and scaled-up three important global public health strategies (i.e., DOTS, Stop TB, and End TB) to improve the international scenario.
Sotgiu G., Sulis G., Matteelli A.
openaire   +3 more sources