Results 41 to 50 of about 3,588,358 (362)

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

FEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos, Doriana Ricciuti, Giada Mondanelli, Marco Gargaro   +3 more
wiley   +1 more source

A circulating vaccine-derived poliovirus type 2 outbreak in a chronic conflict setting: a descriptive epidemiological study in South Sudan – 2020 to 2021

BMC Infectious Diseases, 2023
Background In this study, we describe the epidemiological profile of an outbreak of the circulating Vaccine Derived Polio Virus type 2 in South Sudan from 2020 to 2021. Method We conducted a retrospective descriptive epidemiological study using data from
Ayesheshem Ademe Tegegne, Atem Nathan Anyuon, George Awzenio Legge, Melisachew Adane Ferede, Zingbondo Isaac, Kirbak Anthony Laku, Sibhatu Biadgilign, Ochan Taban David Kilo, Fabian Ndenzako, Ndoutabe Modjirom, Olushayo Oluseun Olu, Sylvester Maleghemi   +11 more
doaj   +1 more source

World Report on Disability, Chapter 8: Work and Employment [PDF]

, 2011
Across the world, people with disabilities are entrepreneurs and selfemployed workers, farmers and factory workers, doctors and teachers, shop assistants and bus drivers, artists, and computer technicians (1).
Cornell University, World Health Organization, World Bank
core   +1 more source

Health promotion by communities and in communities: current issues for research and practice. [PDF]

, 2014
BACKGROUND AND AIMS: This paper explores contemporary issues around community-based health promotion in the light of international health policies reaffirming the central role of community action within broader efforts to achieve health equity.
Foot J, Friedli L, Kickbusch I, National Institute for Health and Clinical Excellence, South J, White J, World Health Organization, World Health Organization, World Health Organization   +8 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Why has the health promoting prison concept failed to translate to the US? [PDF]

, 2018
Two decades since the World Health Organization Regional Office for Europe published a report on health promotion in prison that stimulated further debate on the concept of the “health-promoting prison,” this article discusses the extent to which the ...
Henrichson C, Walmsley R, Woodall J, Woodall J, World Health Organization, World Health Organization   +5 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Planning to improve global health: the next decade of tuberculosis control

Bulletin of the World Health Organization, 2007
The Global Plan to Stop TB 2006-2015 is a road map for policy-makers and managers of national programmes. It sets out the key actions needed to achieve the targets of the Millennium Development Goals relating to tuberculosis (TB): to halve the prevalence
Dermot Maher, Chris Dye, Katherine Floyd, Andrea Pantoja, Knut Lonnroth, Alasdair Reid, Eva Nathanson, Thad Pennas, Uli Fruth, Jane Cunningham, Heather Ignatius, Mario C Raviglione, Irene Koek, Marcos Espinal   +13 more
doaj  

A global framework for action to improve the primary care response to chronic non-communicable diseases: a solution to a neglected problem. [PDF]

, 2009
BACKGROUND: Although in developing countries the burden of morbidity and mortality due to infectious diseases has often overshadowed that due to chronic non-communicable diseases (NCDs), there is evidence now of a shift of attention to NCDs.
AD Harries, AD Harries, Anthony D Harries, AS Daar, B Janssens, D Maher, D Maher, D Maher, D Sanders, D Wilkinson, Dermot Maher, Don Enarson, H Coovadia, J Zarocostas, JL Haggerty, K Strong, M Chan, M Suhrcke, N Ait-Khaled, N Sewankambo, O Adeyi, PW Setel, R Beaglehole, R Beaglehole, R Magnusson, Rony Zachariah, SM Tollman, TW Mahungu, World Diabetes Foundation, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, World Health Organization, UNAIDS, UNICEF   +34 more
core   +3 more sources