Results 61 to 70 of about 3,588,358 (362)

Requirements for Diagnosis of Malaria at Different Levels of the Laboratory Network in Africa. [PDF]

open access: yes, 2009
The rapid increase of resistance to cheap, reliable antimalarials, the increasing cost of effective drugs, and the low specificity of clinical diagnosis has increased the need for more reliable diagnostic methods for malaria.
Barnish   +5 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Putting evolution in elimination: Winning our ongoing battle with evolving malaria mosquitoes and parasites [PDF]

open access: yes, 2018
Since 2000, the world has made significant progress in reducing malaria morbidity and mortality, and several countries in Africa, South America and South-East Asia are working hard to eliminate the ...
Hamilton W. L.   +14 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Global data on visual impairment in the year 2002

open access: yesBulletin of the World Health Organization, 2004
This paper presents estimates of the prevalence of visual impairment and its causes in 2002, based on the best available evidence derived from recent studies. Estimates were determined from data on low vision and blindness as defined in the International
Serge Resnikoff   +6 more
doaj  

rVSV-ZEBOV vaccination in people with pre-existing immunity to Ebolavirus: an open-label safety and immunogenicity study in Guinean communities affected by Ebola virus disease (l’essai proches)

open access: yesBMC Medicine
Background Zaire Ebolavirus disease (EVD) outbreaks can be controlled using rVSV-ZEBOV vaccination and other public health measures. People in high-risk areas may have pre-existing antibodies from asymptomatic Ebolavirus exposure that might affect ...
Conall H. Watson   +36 more
doaj   +1 more source

Can non-physician health-care workers assess and manage cardiovascular risk in primary care?

open access: yesBulletin of the World Health Organization
OBJECTIVE: To ascertain the reliability of applying the WHO Cardiovascular Risk Management Package by non-physician health-care workers (NPHWs) in typical primary health-care settings.
Dele O Abegunde   +7 more
doaj   +1 more source

Maternity waiting homes in Southern Lao PDR : the unique \u27silk home\u27

open access: yes, 2008
The concept of maternity waiting homes (MWH) has a long history spanning over 100 years. The research reported here was conducted in the Thateng District of Sekong Province in southern Lao People’s Democratic Republic (PDR) to establish whether the
AbouZahr   +12 more
core   +1 more source

Naming the coronavirus disease (COVID-19) and the virus that causes it [PDF]

open access: yes, 2020
This article is a sharing of information linked to the World Health Organization website. For more information, the reader can access the WHO website through this link: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance ...
World Health Organization   +1 more
core   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

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