Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Romėnų teatras ir Senekos tragedijos: Pamišęs Herkulis, Edipas. The Roman theatre and Seneca’s tragedies Hercules Furens, Oedipus [PDF]
The article analyses the feelings of characters in Seneca’s tragedies prior and after recognising their guilt. Expression of the feelings of the characters in Seneca’s two tragedies Hercules Furens and Oedipus is compared, features characteristic of ...
Jovita Dikmonienė
doaj
Fire in the Soul of Zurga: Bizet\u27s The Pearl Fishers and Male Sati [PDF]
In lieu of an abstract, below is the essay\u27s first paragraph. Although in recent years Georges Bizet’s “other” opera, Les Pêcheurs de perles (The Pearl Fishers), has been performed on occasion, scant attention has been paid to it, compared to his ...
Dabbagh, Lori
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The Comic Image of the Courtly Love Ideals in Le Morte D’Arthur by Sir Thomas Malory [PDF]
The Arthurian legends have fascinated and inspired people for ages. Le Morte D’Arthur by Sir Thomas Malory is one of the best compilations of the stories about King Arthur and his peers.
Mrówka, Aleksandra
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Przemiany bohatera w powojennym kinie polskim – od Supermana do Wonder Woman
The article presents the evolution of the heroes in Polish cinema after the Second World War, as well as while showing the characters that influenced the social awareness of Poles, it reveals those which have been created in response to the social needs.
Agnieszka Tambor
doaj
Homebound: STS-M1301 A Study on Television Writing in the Science Fiction Genre [PDF]
This project is a scene-by-scene outline of an original television pilot script in the science fiction genre. The outline is based on research conducted in both the television and science fiction fields, providing the project with a firm foundation in ...
Crouch, Matthew
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Художественная картина мира в романе Лены Элтанг «Каменные клены»| Meninis pasaulėvaizdis Lenos Eltang romane „Akmeniniai klevai“ | Artistic picture of the world in the novel “The stone maples” by Lena Eltang [PDF]
The article deals with the category of the “artistic picture of the world” and analyzes the way and elements of the personal thinking and world perception of Lena Eltang, which are reflected in her novel “The Stone Maples”.
Galina Mikhailova, Aleksandra Samoylenko
doaj

