Results 71 to 80 of about 1,878,464 (266)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Abstracts of the Main Papers presented during the 8th World Rabbit Congress, Puebla, Mexico 7-10, 2004 [PDF]
, 2005 World Rabbit Science (2005). Abstracts of the Main Papers presented during the 8th World Rabbit Congress, Puebla, Mexico 7-10, 2004. World Rabbit Science. 14(2).
World Rabbit Science
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Comment on “Methodology of Marx’s world history thought”
Trans/Form/AçãoCommented article: WU, Haicui. Methodology of Marx’s world history thought. Trans/Form/Ação: Unesp journal of philosophy, Marília, v. 47, n. 5, “Eastern thought 2”, e02400151, 2024. Available at: https://revistas.marilia.unesp.br/index.php/transformacao/
Tingting Chai
doaj +1 more source
IEEE Access, 2018 As a dedicated countermeasure for heterogeneous multi-view data, multi-view clustering is currently a hot topic in machine learning. However, many existing methods either neglect the effective collaborations among views during clustering or do not ...
Pengjiang Qian +7 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Acta Theologica, 2016 In Africa, the whole are religious and the dead are believed to be actively involved in the daily affairs of the people. Such a worldview, in which the Sacred Other, the living and the (living) dead formed an integral whole, can also be observed at ...
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
World Bank Group Scorecard FY24
This document presents three different views of the WBG scorecard: 1. Scorecard view presents all data at the WBG level for a set of 50 indicators (8 Vision indicators, 22 Client Context indicators, and 20 ...
World Bank
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World Development Indicators 2017
, 2017 This year the World Development Indicators database has been improved to include more indicators that cover the Sustainable Development Goals and more data disaggregated by sex, age, wealth quintile, and urban or rural location.
World Bank
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