Results 81 to 90 of about 1,878,464 (266)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
World Bank Group Scorecard FY2025
This document presents three different views of the World Bank Group (WBG) Scorecard: (1) WBG scorecard view presents all data at the WBG level for a set of 51 indicators (8 Vision indicators, 22 Client Context indicators, and 21 WBG Results indicators).
World Bank Group
core +2 more sources
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Argentine Youth : An Untapped Potential
Argentina's youth, 6.7 million between the ages of 15 and 24, are an important, but to a certain extent untapped, resource for development.
World Bank
core +1 more source
Zagadnienie wolności osoby ludzkiej w ujęciu Leibniza (THE PROBLEM OF HUMAN FREEDOM ACCORDING TO LEIBNIZ) [PDF]
The article concerns the fundamental metaphysical problem of human freedom as it is discussed in Leibniz's philosophy. The essence of it can be expressed as follows: in what way the determinism developed by Leibniz goes along with his doctrine of human ...
Przemysław Gut
doaj
NEW LIFE FROM A PASTORAL TEXT OF TERROR? GENDER PERSPECTIVES ON GOD AND HUMANITY IN 1 TIMOTHY 2
Amidst threatening pseudo-practices, 1 Timothy seems to be concerned mainly with the integrity of the Christian gospel within the larger Greco-Roman society.
Elna Mouton, Ellen Van Wolde
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source

