Results 91 to 100 of about 1,595,501 (315)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Atopic Dermatitis and Autoimmune Connective Tissue Diseases: Systematic Review and Meta-Analysis

Dermatology Practical & Conceptual
Introduction: The association between atopic dermatitis (AD) and autoimmune connective tissue diseases (ACTD) is not well-investigated. Objective: We aimed to conduct a systematic review and meta-analysis to assess the association between AD and ACTD.
Somaia Naassan, Misbah Noshela Ghazanfar, Simon Francis Thomsen, Zarqa Ali   +3 more
doaj   +1 more source

Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review [PDF]

, 2017
Objective: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed.
Bua, N., Carradice, D., Chetter, I.C., Harwood, A.E., Smith, G.E., Totty, J.P., Wallace, T.   +6 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A Photothermally Triggered Nanoplatform for Multidimensional Antibacterial Therapy and Accelerated Healing of Infected Wounds

International Journal of Nanomedicine
Yueying Fan,1,* Jinfu Li,1,* Peng Wang,1,* Yuhuan Peng,1 Chao Yan,1 Xiangyang Li,1 Zhaoxiang Wang,1 Xiao Li,1 Zhanchen He,1 Wenqiang Li,2 Bin Yin,1 Chiyu Jia1 1Center of Burn & Plastic and Wound Healing Surgery, The First ...
Fan Y, Li J, Wang P, Peng Y, Yan C, Li X, Wang Z, Li X, He Z, Li W, Yin B, Jia C   +11 more
doaj  

Multifunctional hydrogel targeting senescence to accelerate diabetic wound healing through promoting angiogenesis

Journal of Nanobiotechnology
Diabetic wound healing remains a significant clinical challenge because of hyperglycaemia-induced cellular senescence, impaired angiogenesis, and chronic inflammation. To address these issues, we developed a multifunctional hydrogel (GelMA/PNS/Alg@IGF-1)
Hao Yang, Yongfei Chen, Yanchao Rong, Yuxi Zhou, Shuting Li, Xiaohui Li, Honglin Wu, Dongming Lv, Xiaoling Cao, Peng Wang, Jiayuan Zhu, Bing Tang, Zhicheng Hu   +12 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

CHRONIC WOUNDS

Surgical Clinics of North America, 1997
Skin ulcers are the most common chronic wounds. Current management principles and theories of causation of the most common ulcers--pressure, diabetic, and venous--are described. Issues related to occlusive dressings, compression dressings, topical antimicrobials, debridement, growth factors, grafting, and bioengineered tissue therapy are discussed ...
W H, Eaglstein, V, Falanga
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source