Results 81 to 90 of about 1,595,501 (315)

Guselkumab for hidradenitis suppurativa in a patient with concomitant Crohn’s disease: Report and systematic literature review of effectiveness and safety

open access: yesClinical Case Reports, 2020
Guselkumab appears to be safe and effective in the treatment of patients with HS, who do not respond to adalimumab and other systemic therapies. Guselkumab can be used in patients with comorbid Crohn's disease.
Astrid‐Helene Ravn Jørgensen   +2 more
doaj   +1 more source

The Roles of Physical Therapists in Wound Management: Part IV [PDF]

open access: yes, 2009
Physical therapists are important members of the comprehensive wound management team. In addition to being able to provide standard wound care, they are well prepared to treat wounds with a variety of biophysical agents that introduce electromagnetic ...
Kloth, Luther C.
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Fatal outcome of malignant transformation of hidradenitis suppurativa: A case report and literature review

open access: yesClinical Case Reports, 2020
Squamous cell carcinoma arising in hidradenitis suppurativa (HS) is a rare albeit the most serious complication in HS, with a reported fatality of up to 42.9%. This calls for greater clinical awareness in patients with long‐standing chronic HS.
Valdemar Wendelboe Nielsen   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Celiac Disease and Skin Diseases: A Bidirectional Mendelian Randomization Study

open access: yesClinical, Cosmetic and Investigational Dermatology
Chenyang Ge,1 Yizheng Wang,2 Xuegang Zhao,1 Jiawen Hao,1 Jing Zhang,1 Mengyuan Lu,1 Congying Li,1 Jianke Feng,1 Qingfu Zhang1 1Burn and Wound Repair Center, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, 050000, People’s Republic of China;
Ge C   +8 more
doaj  

A survey of nurses' and podiatrists' attitudes, skills and knowledge of lower extremity wound care [PDF]

open access: yes, 2008
Published literature has identified deficits in the wound care knowledge of many healthcare professionals involved in tissue viability, which may suggest some patients are receiving suboptimal care.
McIntosh, Caroline, Ousey, Karen
core  

Exploring Resilience When Living with a Wound — An Integrative Literature Review [PDF]

open access: yes, 2014
The psychological impact for patients with wounds can be significant, and adverse psychological effects frequently occur when there are permanent changes in the body’s structure or function.
Edward, Karen-Leigh, Ousey, Karen
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Novel locally active estrogens accelerate cutaneous wound healing-part 2 [PDF]

open access: yes, 2017
Estrogen deprivation is associated with delayed healing, while estrogen replacement therapy (ERT) accelerates acute wound healing and protects against development of chronic wounds.
Bartoli, Gabriele   +12 more
core   +2 more sources

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