Results 61 to 70 of about 730,768 (269)

A Photothermally Triggered Nanoplatform for Multidimensional Antibacterial Therapy and Accelerated Healing of Infected Wounds

International Journal of Nanomedicine
Yueying Fan,1,* Jinfu Li,1,* Peng Wang,1,* Yuhuan Peng,1 Chao Yan,1 Xiangyang Li,1 Zhaoxiang Wang,1 Xiao Li,1 Zhanchen He,1 Wenqiang Li,2 Bin Yin,1 Chiyu Jia1 1Center of Burn & Plastic and Wound Healing Surgery, The First ...
Fan Y, Li J, Wang P, Peng Y, Yan C, Li X, Wang Z, Li X, He Z, Li W, Yin B, Jia C   +11 more
doaj  

Atopic Dermatitis and Autoimmune Connective Tissue Diseases: Systematic Review and Meta-Analysis

Dermatology Practical & Conceptual
Introduction: The association between atopic dermatitis (AD) and autoimmune connective tissue diseases (ACTD) is not well-investigated. Objective: We aimed to conduct a systematic review and meta-analysis to assess the association between AD and ACTD.
Somaia Naassan, Misbah Noshela Ghazanfar, Simon Francis Thomsen, Zarqa Ali   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Research on the Role of Autophagy in Vascular Endothelial Cells in the Healing of Chronic Refractory Wounds

Biologics: Targets & Therapy
Lao Riling,1 Fan Kunyue,1 Gan Liyan,2 Wang Yaya,1 Ni Baoling,1 Li Jiehui3 1Department of Wound Repair Surgery,Guangxi Province Hospital, Guangxi University of Traditional Chinese Medicine, Nan Ning, Guang Xi, People’s Republic of China; 2Department of ...
Riling L, Kunyue F, Liyan G, Yaya W, Baoling N, Jiehui L   +5 more
doaj  

Bioactive glass 1393 promotes angiogenesis and accelerates wound healing through ROS/P53/MMP9 signaling pathway

Regenerative Therapy
Compared to bioactive glass 45S5, bioactive glass 1393 has shown greater potential in activating tissue cells and promoting angiogenesis for bone repair. Nevertheless, the effect of bioactive glass 1393 in the context of wound healing remains extensively
Xuenan Chen, Xinyu Ran, Xuebo Wei, Lifei Zhu, Shaodong Chen, Zhiyong Liao, Ke Xu, Weidong Xia   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hybrid hydrogel based on porcine-derived matrix with gallic acid and cerium-doped mesoporous bioactive glass for diabetic wound healing

Materials & Design
Macrophage aggregation and excessive inflammation are prevalent issues in diabetic wounds, often resulting in impaired wound healing. Consequently, hydrogel dressings with immunomodulatory properties hold significant potential for clinical application in
Hao Zeng, Qinghong Lai, Wuqiang Liao, Jiajin Tu, Junfeng Sun   +4 more
doaj   +1 more source