Results 41 to 50 of about 1,595,501 (315)

A multiscale hybrid mathematical model of epidermal-dermal interactions during skin wound healing. [PDF]

, 2019
Following injury, skin activates a complex wound healing programme. While cellular and signalling mechanisms of wound repair have been extensively studied, the principles of epidermal-dermal interactions and their effects on wound healing outcomes are ...
Chen, Weitao, Du, Huijing, Figueroa, Seth, Guerrero-Juarez, Christian F, Nie, Qing, Plikus, Maksim V, Qiu, Yuchi, Wang, Yangyang   +7 more
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

The time-dependent localization of Ki 67 antigen-positive cells in human skin wounds [PDF]

, 1993
A total of 77 human skin wounds with a post-infliction interval between 3 h and 7 months were investigated and the proliferation marker antigen Ki 67 was visualized in paraffin sections using a specific monoclonal antibody (MIB).
A. Nerlich, DC Brown, E Ralfkiaer, EA Hell, H Cottier, J Gerdes, J Gerdes, J-P Ortonne, J. T�bel, J. Wilske, JL Cordell, M Oehmichen, M Oehmichen, P Betz, P Betz, P Betz, P Block, P. Betz, R Ross, R. Penning, RMM McMinn, RV Vito De, W. Eisenmengen   +22 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Silver nanoparticle loaded collagen/chitosan scaffolds promote wound healing via regulating fibroblast migration and macrophage activation

Scientific Reports, 2017
Treatment of full-thickness skin defects poses significant clinical challenges including risk of infection and severe scaring. Silver nanoparticle (NAg), an effective antimicrobial agent, has provided a promising therapeutic method for burn wounds ...
Chuangang You, Qiong Li, Xingang Wang, Pan Wu, Jon Kee Ho, Ronghua Jin, Liping Zhang, Huawei Shao, Chunmao Han   +8 more
doaj   +1 more source

Correlation between Insulin Resistance and Microalbuminuria Creatinine Ratio in Postmenopausal Women

International Journal of Endocrinology, 2022
Objective. To study the relationship between insulin resistance and urinary microalbumin creatinine ratio in postmenopausal women. Methods. The selected research group comprised 104 postmenopausal women with type 2 diabetes who were admitted to the ...
Han Na, Rong Wang, Hai-Long Zheng, Xiao-Pan Chen, Lin-Yang Zheng   +4 more
doaj   +1 more source

Macrophages in wound healing: activation and plasticity. [PDF]

, 2019
Macrophages are critically involved in wound healing, from dampening inflammation to clearing cell debris and coordinating tissue repair. Within the wound, the complexity of macrophage function is increasingly recognized, with adverse outcomes when ...
Kim, Sang Yong, Nair, Meera G
core  

Validation of ICD-9-CM diagnosis codes for surgical site infection and noninfectious wound complications after mastectomy [PDF]

, 2016
BACKGROUNDFew studies have validated ICD-9-CM diagnosis codes for surgical site infection (SSI), and none have validated coding for noninfectious wound complications after mastectomy.OBJECTIVESTo determine the accuracy of International Classification of ...
Ball, Kelly E, Fraser, Victoria J, Nickel, Katelin B, Olsen, Margaret A, Wallace, Anna E   +4 more
core   +2 more sources

Optomagnetic Imaging Spectroscopy (OMIS) for in situ detection of bacteria in blood – feasibility study

4 open, 2022
Introduction: Sepsis is one of the leading causes of death in military and civilian hospitals. Rapid identification of involved pathogens is a key step for appropriate diagnosis, treatment and ultimately survival.
Garry Brittany, Stoiljkovic Nikola, Jovic Zorana, Pavlovic Radmila, Getnet Derese, Demons Samandra T., Tyner Stuart D., Zurawski Daniel V., Swierczewski Brett E., Koruga Djuro, Bobrov Alexander G., Antonic Vlado   +11 more
doaj   +1 more source

Collective cell migration: Implications for wound healing and cancer invasion. [PDF]

, 2013
During embryonic morphogenesis, wound repair and cancer invasion, cells often migrate collectively via tight cell-cell junctions, a process named collective migration.
He, Yong, Jiang, Jianxin, Li, Li, Zhao, Min   +3 more
core   +2 more sources