Results 41 to 50 of about 725,199 (269)
A Comprehensive Review: Advances in Mesenchymal Stem Cell Applications for Burn Wound Repair
Stem Cells InternationalTissue repair following skin injury is a complex process that encompasses hemostasis, inflammation, tissue cell proliferation, and structural remodeling.
Hui-Juan Zhang +5 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Wounds – From Physiology to Wound Dressing [PDF]
Deutsches Ärzteblatt international, 2008 Optimal wound management remains the subject of active research. Improved knowledge of physiological wound healing, systemic research into wound dressing and the evaluation of chemical disinfection have given rise to new approaches to wound care.Selective literature review.The primary goals of wound management are rapid wound closure and a functional ...
Peter, Kujath, Angela, Michelsen
openaire +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A retrospective real-world analysis of placental-based allografts on pressure ulcers
SAGE Open MedicineObjective: The records from a network of mobile wound clinics were analyzed to evaluate the efficacy of a human placental-based allograft compared with the standard of care for patients with chronic pressure ulcer wounds and multiple comorbidities ...
David Kay +2 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Comparing Self‐Reported and Physician‐Assessed Acne Severity Using Real‐World Data
JEADV Clinical PracticeBackground Real‐world data (RWD) offers access to vast amounts of health information; however, limited knowledge exists regarding its reliability in clinical and research practices.
Ali Al‐Mousawi +7 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source