Results 31 to 40 of about 1,595,501 (315)

Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds. [PDF]

, 2020
Chronic wounds represent a large and growing disease burden. Infection and biofilm formation are two of the leading impediments of wound healing, suggesting an important role for the microbiome of these wounds.
Chen, Irene A, Deacon, John M, Lee, Juhee, Shen, Yuning, Verbanic, Samuel   +4 more
core   +1 more source

Non-viral gene delivery systems for tissue repair and regeneration

Journal of Translational Medicine, 2018
Critical tissue defects frequently result from trauma, burns, chronic wounds and/or surgery. The ideal treatment for such tissue loss is autografting, but donor sites are often limited.
Pan Wu, Haojiao Chen, Ronghua Jin, Tingting Weng, Jon Kee Ho, Chuangang You, Liping Zhang, Xingang Wang, Chunmao Han   +8 more
doaj   +1 more source

In reply to the letter to the editor regarding “Comparison of a twin interlocking derotation and compression screw cephalomedullary nail (InterTAN) with a single screw derotation cephalomedullary nail (proximal femoral nail antirotation): a systematic review and meta-analysis for intertrochanteric fractures”

Journal of Orthopaedic Surgery and Research, 2022
Background Intertrochanteric hip fractures are common and devastating injuries, especially for the elderly. Surgical treatment is the optimal strategy for managing intertrochanteric fractures as it allows early rehabilitation and functional recovery. The
Leo Nherera, Paul Trueman, Alan Horner, Tracy Watson, Alan J. Johnstone   +4 more
doaj   +1 more source

Klotho mice: a novel wound model of aged skin. [PDF]

, 2014
BackgroundAs the elderly population continues to expand, it becomes increasingly important to develop treatments to improve wound healing in the elderly.
Yamashita, Ken, Yamauchi, Makoto, Yotsuyanagi, Takatoshi, Young, David M   +3 more
core   +2 more sources

Fracture healing in a polytrauma rat model is influenced by mtDNA:cGAS complex mediated pro‐inflammation

Journal of Experimental Orthopaedics, 2023
Purpose The mitochondrial DNA (mtDNA) activated cyclic guanosine monophosphate–adenosine monophosphate synthase—stimulator of interferon genes (cGAS‐STING) signaling pathway is a key player in mediating immune responses in autoimmune disorders and cancer.
Preeti J. Muire, Alicia L. Lofgren, Stefanie M. Shiels, Joseph C. Wenke   +3 more
doaj   +1 more source

Reducing skin tears, workload, and costs in the frail aged: replacing showers with bath cloths

Asian Journal of Medical Sciences, 2022
Background: Two Nurse Consultants, as part of their usual practice of auditing wounds in a 25-bed dementia unit of an aged care facility in Sydney, Australia, reported on skin tears (STs), wounds that occur mainly on the forearms of the elderly and often
Catherine Sharp , Julie Campbell
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Reconstituted high-density lipoproteins promote wound repair and blood flow recovery in response to ischemia in aged mice [PDF]

, 2016
Background: The average population age is increasing and the incidence of age-related vascular complications is rising in parallel. Impaired wound healing and disordered ischemia-mediated angiogenesis are key contributors to age-impaired vascular ...
Bursill, Christina A., Lam, Yuen Ting, Ng, Martin K. C., Ridiandries, Anisyah, Robertson, Stacy, Tan, Joanne T. M., Tsatralis, Tania, Vanags, Laura Z.   +7 more
core   +2 more sources

Dexamethasone for Chemotherapy‐Induced Nausea and Vomiting Prevention in Pediatric Patients: International Consensus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi, Paula D. Robinson, Shana Jacobs, L. Lee Dupuis, the International Pediatric Dexamethasone Panel, Sameer Bakhshi, Tiene Bauters, Eva Brack, Simone Cesaro, Claire Fosbrook, Jason Freedman, Tamara MacDonald, Eloise Neumann, Venkatraman Radhakrishnan, Rod Rassekh, Florian Slimano, Johnathan Soggee, Joel Thompson, Marianne van de Wetering, Milena Villarroel, Jasper Wong   +20 more
wiley   +1 more source

Cantharanthus Roseus Leaf Extract Accelerates Healing Of Wound Wistar Rat [PDF]

, 2013
Cantharantus roseus (C. roseus) is a medical plant that has been used to treat various diseases. This study was carried to determine C. roseus leaf extract able to acclerate wound healing in Wistar rat. Full skin-tickness round wounds were created on the
Anom-Dada, I. K. (I), Berata, I. K. (I), Damriyasa, A. I. (and), Putra-Manuaba, I. B. (I)   +3 more
core