Results 11 to 20 of about 572,176 (313)

Knockout of cytochrome P450 1A1 enhances lipopolysaccharide‐induced acute lung injury in mice by targeting NF‐κB activation

FEBS Open Bio, 2020
Acute lung injury (ALI) is accompanied by overactivation of multiple pro‐inflammatory factors. Cytochrome P450 1A1 (CYP1A1) has been shown to aggravate lung injury in response to hyperoxia. However, the relationship between CYP1A1 and lipopolysaccharide (
Li‐xing Tian, Xin Tang, Wei Ma, Jing Wang, Wei Zhang, Kuan Liu, Tao Chen, Jun‐yu Zhu, Hua‐ping Liang   +8 more
doaj   +1 more source

Biofilm exacerbates antibiotic resistance: Is this a current oversight in antimicrobial stewardship?

Antimicrobial Resistance and Infection Control, 2020
Objective To raise awareness of the role of environmental biofilm in the emergence and spread of antibiotic resistance and its consideration in antimicrobial stewardship. Background Antibiotic resistance is a major threat to public health.
Philip Bowler, Christine Murphy, Randall Wolcott   +2 more
doaj   +1 more source

Integrated bioinformatical and in vitro study on drug targets for liver cirrhosis based on unsupervised consensus clustering and immune cell infiltration

Frontiers in Pharmacology, 2023
Liver cirrhosis is one of the most common cause of death in the world. The progress of liver cirrhosis involves health, liver cirrhosis and liver cancer, leading to great challenges in the diagnosis of the disease.
Qingjia Chi, Qingjia Chi, Di Wang, Ting Sun, Hua-Ping Liang   +4 more
doaj   +1 more source

Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review [PDF]

, 2017
Objective: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed.
Bua, N., Carradice, D., Chetter, I.C., Harwood, A.E., Smith, G.E., Totty, J.P., Wallace, T.   +6 more
core   +2 more sources

Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds. [PDF]

, 2020
Chronic wounds represent a large and growing disease burden. Infection and biofilm formation are two of the leading impediments of wound healing, suggesting an important role for the microbiome of these wounds.
Chen, Irene A, Deacon, John M, Lee, Juhee, Shen, Yuning, Verbanic, Samuel   +4 more
core   +1 more source

Humidified Warmed CO2 Treatment Therapy Strategies Can Save Lives With Mitigation and Suppression of SARS-CoV-2 Infection: An Evidence Review

Frontiers in Medicine, 2020
The coronavirus disease (COVID-19) outbreak has presented enormous challenges for healthcare, societal, and economic systems worldwide. There is an urgent global need for a universal vaccine to cover all SARS-CoV-2 mutant strains to stop the current ...
Alaa M. M. El-Betany, Enas M. Behiry, Mark Gumbleton, Keith G. Harding   +3 more
doaj   +1 more source

Risk Factors of Surgical Site Infection at Muhimbili National Hospital, Dar es Salaam, Tanzania [PDF]

, 2012
Surgical site infection (SSI) is a common source of morbidity among operated patients. At Muhimbili National Hospital (MNH), studies indicate that the rate of SSI has been increasing over the past thirty years.
Akoko, L.O., Fredrick, F., Mbembati, N.M., Mwanga, A.H.   +3 more
core   +2 more sources

Laboratory evaluation of Drawtex Hydroconductive Dressing with LevaFiber technology [PDF]

, 2014
Good wound bed preparation is an essential aspect of wound care and effective wound healing. Removal of dead and necrotic tissue either through autolytic or interventional debridement, followed by good exudate management, inhibition of matrix ...
Edwards-Jones, Valerie, School of Engineering, Manchester Metropolitan University, UK, School of Research, Enterprise and Innovation, Manchester Metropolitan University, Manchester, UK, Spruce, Pam, TVRE Consulting. Stoke on Trent, UK, Vishnyakov, Vladimir   +5 more
core   +1 more source

A Host-Directed Approach to the Detection of Infection in Hard-to-Heal Wounds

Diagnostics, 2022
Wound infection is traditionally defined primarily by visual clinical signs, and secondarily by microbiological analysis of wound samples. However, these approaches have serious limitations in determining wound infection status, particularly in early ...
Michael Burnet, Daniel G. Metcalf, Scarlet Milo, Clemens Gamerith, Andrea Heinzle, Eva Sigl, Kornelia Eitel, Marieke Haalboom, Philip G. Bowler   +8 more
doaj   +1 more source

A preliminary study of the effect of closed incision management with negative pressure wound therapy over high-risk incisions [PDF]

, 2015
Background Certain postoperative wounds are recognised to be associated with more complications than others and may be termed high-risk. Wound healing can be particularly challenging following high-energy trauma where wound necrosis and infection ...
A Colli, A Koski, A Li, A Wackenfors, A Wackenfors, AE Guille, BJ Stanley, CJ Jordan, D Herscovici Jr, DA Mendonca, David M. R. Sajik, DR Holt, DV Kipaldi, E Krug, EJ Harvey, EJ Timmenga, GI Taylor, GK Berry, GW Stanway, J Bertran, J Compston, J Kanis, JC Murrell, JP Stannard, JP Stannard, JS Weese, JT Thompson, JW Fox, Karen L. Perry, KV Lambert, L Holton, LJ Owen, Lynda Rutherford, M Demaria, M Pachowsky, MF Fay, Mieghan Bruce, MJ Allen, MJ Morykwas, MJ Morywkas, MJ Morywkas, MW Bohling, MW Bohling, N Fitzpatrick, NA Abidi, PC Bristow, PE Banwell, PE Banwell, PM Taylor, R Ben Amotz, R Burkhardt, R Petzina, RP Wilkes, S Karlakki, S Lindstedt, SA Robertson, SP Roch, SZ Chen, TJ Smith, WT DeCarbo   +59 more
core   +3 more sources