Results 21 to 30 of about 340,433 (264)

Comparative study between mass closure suturing technique and Hughes repair in emergency midline laparotomies

Asian Journal of Medical Sciences, 2023
Background: The most alarming post-operative consequences for patients and doctors are wound infection and dehiscence. Post-operative wound infection and dehiscence lengthen the hospital stay after surgery.
Mukesh Kumar P , Sathyaraj P , Jemin Bharath R , Ramprasath S , Renganathan M   +4 more
doaj   +1 more source

Lipidomic and transcriptional analysis of the linoleoyl-omega-hydroxyceramide biosynthetic pathway in human psoriatic lesions

Journal of Lipid Research, 2021
A complex assembly of lipids including fatty acids, cholesterol, and ceramides is vital to the integrity of the mammalian epidermal barrier. The formation of this barrier requires oxidation of the substrate fatty acid, linoleic acid (LA), which is ...
Victoria J. Tyrrell, Faraz Ali, William E. Boeglin, Robert Andrews, James Burston, James C. Birchall, John R. Ingram, Robert C. Murphy, Vincent Piguet, Alan R. Brash, Valerie B. O'Donnell, Christopher P. Thomas   +11 more
doaj   +1 more source

Subacute postoperative endophthalmitis secondary to sutureless self-sealing corneal wound infection at both main cornea and side port wounds: A case report

Indian Journal of Ophthalmology. Case Reports, 2021
Corneal wound infection following cataract surgery is rare. We describe a case of wound infection at both the main wound and the side port wound following uncomplicated phacoemulsification.
Ngu DB Michael, Ye Y Kueh
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Dexmedetomidine alleviates sepsis-associated acute kidney injury by inhibiting renal tubular ferroptosis via JNK/MAPK–LCN2 pathway

European Journal of Medical Research
Background Sepsis-associated acute kidney injury (SA-AKI), one of the most common complications of sepsis, significantly prolongs hospitalization, increases mortality, and elevates risks of cardiovascular events and chronic kidney disease.
Boyang Liu, Shengxiang Ao, Li Luo, Lin Qiao, Tianyin Kuang, Hongyan Xiao, Jing Zhou, Shuangqin Yin, Huaping Liang, Fen Li, Weihong Dai, Junyu Zhu   +11 more
doaj   +1 more source

Analysis of risk factors for wound infection after extremity fracture caused by machete cut in a resource-limited setting

African Journal of Emergency Medicine, 2022
Background: Machete cut fracture is a unique subset of open fracture. The sharp force of a wielded machete that cleanly divides soft tissue envelope with minimal or no contusion results in an open fracture wound that is relatively less prone to infection.
Njoku Isaac Omoke, Christian Chukwuemeka Madubueze, Francis Ndubuisi Ahaotu, Chinedu Gregory Nwigwe, Anthony Anakweze Anagor, Peace Ifeoma Amaraegbulam, Agama Nnachi Egwu, Omolade Ayoola Lasebikan   +7 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Animal‐Assisted Activities With Therapy Dogs in Pediatric Oncology: A Multicenter Survey of the Current Status, Implementation, and Challenges in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Animal‐assisted activities (AAAs) with therapy dogs have shown positive effects on patient well‐being and quality of life in various areas of medicine, including pediatric oncology. However, research on this topic is limited. The aim of this study is to present the current status of AAA in pediatric oncology in Germany, Austria, and
Jan‐Marius Wedig, Birgit Burkhardt, Christof M. Kramm, Kira Ostermann, Sarah C. Goretzki, Uta Dirksen, Nico Kurpiers, Michael M. Schündeln   +7 more
wiley   +1 more source

Punicalagin as a novel selective aryl hydrocarbon receptor (AhR) modulator upregulates AhR expression through the PDK1/p90RSK/AP-1 pathway to promote the anti-inflammatory response and bactericidal activity of macrophages

Cell Communication and Signaling
Aryl hydrocarbon receptor (AhR) plays an important role in inflammation and immunity as a new therapeutic target for infectious disease and sepsis.
Weihong Dai, Shuangqin Yin, Fangjie Wang, Tianyin Kuang, Hongyan Xiao, Wenyuan Kang, Caihong Yun, Fei Wang, Li Luo, Shengxiang Ao, Jing Zhou, Xue Yang, Chao Fan, Wei Li, Dongmei He, He Jin, Wanqi Tang, Lizhu Liu, Rixing Wang, Huaping Liang, Junyu Zhu   +20 more
doaj   +1 more source

Association of ABCB1 gene polymorphisms rs1128503, rs2032582, rs4148738 with anemia in patients receiving dabigatran after total knee arthroplasty

Chinese Journal of Traumatology
Purpose: Dabigatran is usually prescribed in recommended doses without monitoring of the blood coagulation for the prevention of venous thromboembolism after joint arthroplasty. ABCB1 is a key gene in the metabolism of dabigatran etexilate.
Alina Kasimova, Dmitry Labutin, Anton Gvozdetsky, Svetlana Bozhkova   +3 more
doaj   +1 more source