Results 41 to 50 of about 2,574,127 (301)

Evolution of the wound infection continuum [PDF]

, 2018
In 2016, the International Wound Infection Institute reviewed the wound infection continuum through a literature review and formal Delphi process. This article discusses some significant changes made to the wound infection continuum, including changes in
Haesler, Emily, Ousey, Karen; id_orcid
core   +5 more sources

Punicalagin as a novel selective aryl hydrocarbon receptor (AhR) modulator upregulates AhR expression through the PDK1/p90RSK/AP-1 pathway to promote the anti-inflammatory response and bactericidal activity of macrophages

Cell Communication and Signaling
Aryl hydrocarbon receptor (AhR) plays an important role in inflammation and immunity as a new therapeutic target for infectious disease and sepsis.
Weihong Dai, Shuangqin Yin, Fangjie Wang, Tianyin Kuang, Hongyan Xiao, Wenyuan Kang, Caihong Yun, Fei Wang, Li Luo, Shengxiang Ao, Jing Zhou, Xue Yang, Chao Fan, Wei Li, Dongmei He, He Jin, Wanqi Tang, Lizhu Liu, Rixing Wang, Huaping Liang, Junyu Zhu   +20 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Association of ABCB1 gene polymorphisms rs1128503, rs2032582, rs4148738 with anemia in patients receiving dabigatran after total knee arthroplasty

Chinese Journal of Traumatology
Purpose: Dabigatran is usually prescribed in recommended doses without monitoring of the blood coagulation for the prevention of venous thromboembolism after joint arthroplasty. ABCB1 is a key gene in the metabolism of dabigatran etexilate.
Alina Kasimova, Dmitry Labutin, Anton Gvozdetsky, Svetlana Bozhkova   +3 more
doaj   +1 more source

INCIDENCE OF CAESAREAN WOUND INFECTION IN PATAN HOSPITAL, NEPAL

Journal of Nepal Medical Association, 2003
This study aims to find the incidence and outcome of caesarean wound infection in Patan Hospital, during March 2002 to January 2003. We retrospectively analyzed records of patient who developed wound infection following caesarean section.
Anil Pandit, P Sharma, K Yangzom
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Medical honey for wound care—Still the ‘Latest Resort’? [PDF]

, 2008
While the ancient Egyptians and Greeks used honey for wound care, and a broad spectrum of wounds are treated all over the world with natural unprocessed honeys from different sources, Medihoney™ has been one of the first medically certified honeys ...
Santos, Kai, Molan, Peter C., Gisela Blaser, Udo Bode, Blaser, Gisela, Traynor, Kristen, Kai Santos, Bode, Udo, Kirsten Traynor, Simon, Arne, Arne Simon, Peter Molan   +11 more
core   +2 more sources

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

FREQUENCY AND PATIENT RELATED RISKS FOR SURGICAL SITE INFECTION

Pakistan Armed Forces Medical Journal, 2011
Objective: To determine the frequency of surgical site infection (SSI) and its unknown risk factors in obstetrical and gynaecological procedures. Study Design: Descriptive study Place and Duration of Study: Obstetrics and Gynaecology department of ...
Shahida , Arshad Meo, Saadia Siddique ., Qudsia Nawaz ., Raabia Arshad Meo   +3 more
doaj   +1 more source

Infection in conflict wounded [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2011
Although mechanisms of modern military wounding may be distinct from those of ancient conflicts, the infectious sequelae of ballistic trauma and the evolving microbial flora of war wounds remain a considerable burden on both the injured combatant and their deployed medical systems.
W G P, Eardley, K V, Brown, T J, Bonner, A D, Green, J C, Clasper   +4 more
openaire   +2 more sources