Results 41 to 50 of about 572,176 (313)

Dexmedetomidine alleviates sepsis-associated acute kidney injury by inhibiting renal tubular ferroptosis via JNK/MAPK–LCN2 pathway

European Journal of Medical Research
Background Sepsis-associated acute kidney injury (SA-AKI), one of the most common complications of sepsis, significantly prolongs hospitalization, increases mortality, and elevates risks of cardiovascular events and chronic kidney disease.
Boyang Liu, Shengxiang Ao, Li Luo, Lin Qiao, Tianyin Kuang, Hongyan Xiao, Jing Zhou, Shuangqin Yin, Huaping Liang, Fen Li, Weihong Dai, Junyu Zhu   +11 more
doaj   +1 more source

Does ‘excessive’ anticoagulation predispose to periprosthetic infection? [PDF]

, 2007
Background Although persistent drainage and hematoma formation are recognized risk factors for the development of periprosthetic infection, it is not known if excess anticoagulation is a predisposing factor.
Ghanem, Elie, Hozack, William J., Joshi, Ashish, Parvizi, Javad, Rothman, Richard H., Sharkey, Peter F.   +5 more
core   +2 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

INCIDENCE OF CAESAREAN WOUND INFECTION IN PATAN HOSPITAL, NEPAL

Journal of Nepal Medical Association, 2003
This study aims to find the incidence and outcome of caesarean wound infection in Patan Hospital, during March 2002 to January 2003. We retrospectively analyzed records of patient who developed wound infection following caesarean section.
Anil Pandit, P Sharma, K Yangzom
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Punicalagin as a novel selective aryl hydrocarbon receptor (AhR) modulator upregulates AhR expression through the PDK1/p90RSK/AP-1 pathway to promote the anti-inflammatory response and bactericidal activity of macrophages

Cell Communication and Signaling
Aryl hydrocarbon receptor (AhR) plays an important role in inflammation and immunity as a new therapeutic target for infectious disease and sepsis.
Weihong Dai, Shuangqin Yin, Fangjie Wang, Tianyin Kuang, Hongyan Xiao, Wenyuan Kang, Caihong Yun, Fei Wang, Li Luo, Shengxiang Ao, Jing Zhou, Xue Yang, Chao Fan, Wei Li, Dongmei He, He Jin, Wanqi Tang, Lizhu Liu, Rixing Wang, Huaping Liang, Junyu Zhu   +20 more
doaj   +1 more source

Association of ABCB1 gene polymorphisms rs1128503, rs2032582, rs4148738 with anemia in patients receiving dabigatran after total knee arthroplasty

Chinese Journal of Traumatology
Purpose: Dabigatran is usually prescribed in recommended doses without monitoring of the blood coagulation for the prevention of venous thromboembolism after joint arthroplasty. ABCB1 is a key gene in the metabolism of dabigatran etexilate.
Alina Kasimova, Dmitry Labutin, Anton Gvozdetsky, Svetlana Bozhkova   +3 more
doaj   +1 more source

Understanding effective management of postoperative wounds [PDF]

, 2013
Acute surgical wounds generally heal with no problems. However, some wounds blister around the periwound area and surgical site infection postoperatively, partly due to inappropriate choice of wound dressing.
Ousey, Karen, Roberts, Peter
core  

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Complete Genome and Plasmid Sequences of Staphylococcus aureus EDCC 5055 (DSM 28763), Used To Study Implant-Associated Infections [PDF]

, 2017
Staphylococcus aureus EDCC 5055 (DSM 28763) is a human clinical wound isolate intensively used to study implant-associated infections in rabbit and rat infection models.
Alt, Volker, Bunk, Boyke, Domann, Eugen, Hain, Torsten, Mannala, Gopala Krishna, Overmann, Jörg, Spröer, Cathrin   +6 more
core   +1 more source