Results 21 to 30 of about 4,087,149 (409)

A dual-action peptide-containing hydrogel targets wound infection and inflammation

Science Translational Medicine, 2020
A peptide-containing hydrogel treats both wound infection and inflammation. Double defense Wound infections can increase risk of systemic complications, such as sepsis, and can be difficult to treat due to growing antimicrobial resistance.
M. Puthia, Marta Butrym, J. Petrlova, Ann-Charlotte Strömdahl, M. Å. Andersson, S. Kjellström, A. Schmidtchen   +6 more
semanticscholar   +1 more source

Integrated bioinformatical and in vitro study on drug targets for liver cirrhosis based on unsupervised consensus clustering and immune cell infiltration

Frontiers in Pharmacology, 2023
Liver cirrhosis is one of the most common cause of death in the world. The progress of liver cirrhosis involves health, liver cirrhosis and liver cancer, leading to great challenges in the diagnosis of the disease.
Qingjia Chi, Qingjia Chi, Di Wang, Ting Sun, Hua-Ping Liang   +4 more
doaj   +1 more source

Knockout of cytochrome P450 1A1 enhances lipopolysaccharide‐induced acute lung injury in mice by targeting NF‐κB activation

FEBS Open Bio, 2020
Acute lung injury (ALI) is accompanied by overactivation of multiple pro‐inflammatory factors. Cytochrome P450 1A1 (CYP1A1) has been shown to aggravate lung injury in response to hyperoxia. However, the relationship between CYP1A1 and lipopolysaccharide (
Li‐xing Tian, Xin Tang, Wei Ma, Jing Wang, Wei Zhang, Kuan Liu, Tao Chen, Jun‐yu Zhu, Hua‐ping Liang   +8 more
doaj   +1 more source

Biofilm exacerbates antibiotic resistance: Is this a current oversight in antimicrobial stewardship?

Antimicrobial Resistance and Infection Control, 2020
Objective To raise awareness of the role of environmental biofilm in the emergence and spread of antibiotic resistance and its consideration in antimicrobial stewardship. Background Antibiotic resistance is a major threat to public health.
Philip Bowler, Christine Murphy, Randall Wolcott   +2 more
doaj   +1 more source

Bacteriophages, a New Therapeutic Solution for Inhibiting Multidrug-Resistant Bacteria Causing Wound Infection: Lesson from Animal Models and Clinical Trials

Drug Design, Development and Therapy, 2020
Wound infection kills a large number of patients worldwide each year. Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa are the most important colonizing pathogens of wounds that, with various virulence ...
Majid Taati Moghadam, Amin Khoshbayan, Z. Chegini, Iman Farahani, A. Shariati   +4 more
semanticscholar   +1 more source

Groin wound infection after vascular exposure (GIVE) multicentre cohort study [PDF]

, 2021
Surgical site infections (SSIs) of groin wounds are a common and potentially preventable cause of morbidity, mortality, and healthcare costs in vascular surgery.
Bosanquet, David, Groin Wound Infection after Vascular Exposure (GIVE), Study Group   +1 more
core   +1 more source

Virulence factors and clonal diversity of Staphylococcus aureus in colonization and wound infection with emphasis on diabetic foot infection

European Journal of Clinical Microbiology and Infectious Diseases, 2020
Foot ulcer is a common complication in diabetic subjects and infection of these wounds contributes to increased rates of morbidity and mortality. Diabetic foot infections are caused by a multitude of microbes and Staphylococcus aureus, a major nosocomial
K. Shettigar, T. S. Murali
semanticscholar   +1 more source

Brain magnetic resonance imaging predictors in anti‐N‐methyl‐D‐aspartate receptor encephalitis

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1974-1984, December 2022., 2022
Abstract Objective Brain magnetic resonance imaging (MRI) findings in anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis are nonspecific and rarely have obvious associations with clinical characteristics and outcomes. This study aimed to comprehensively describe the MRI features of patients with NMDAR encephalitis, examine their associations with ...
Ying‐Ying Zhao, Bing Han, Cui‐Hong Qin, Xue‐Xiu Shi, Wen‐Jing Yun, Meng Wang, Bo Yuan, Tong‐Wen Sun, Hai‐Xu Wang   +8 more
wiley   +1 more source

Recognizing early MRI signs (or their absence) is crucial in diagnosing metachromatic leukodystrophy

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1999-2009, December 2022., 2022
Abstract Objectives Metachromatic leukodystrophy (MLD) has characteristic white matter (WM) changes on brain MRI, which often trigger biochemical and genetic confirmation of the diagnosis. In early or pre‐symptomatic disease stages, these typical MRI changes might be absent, hampering early diagnosis.
Daphne H. Schoenmakers, Shanice Beerepoot, Ingeborg Krägeloh‐Mann, Saskia Elgün, Benjamin Bender, Marjo S. van der Knaap, Nicole I. Wolf, Samuel Groeschel   +7 more
wiley   +1 more source

Humidified Warmed CO2 Treatment Therapy Strategies Can Save Lives With Mitigation and Suppression of SARS-CoV-2 Infection: An Evidence Review

Frontiers in Medicine, 2020
The coronavirus disease (COVID-19) outbreak has presented enormous challenges for healthcare, societal, and economic systems worldwide. There is an urgent global need for a universal vaccine to cover all SARS-CoV-2 mutant strains to stop the current ...
Alaa M. M. El-Betany, Enas M. Behiry, Mark Gumbleton, Keith G. Harding   +3 more
doaj   +1 more source