Results 51 to 60 of about 68,858 (291)

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

A STUDY ON DEMOGRAPHIC PROFILE, CLINICAL PRESENTATION AND MANAGEMENT OF CASES WITH PENETRATING ABDOMINAL INJURY

National Journal of Medical Research, 2014
Background: Penetrating abdominal injuries may cause con­siderable troubles at emergency service. The rate of non-therapeutic or negative laparotomy has been reported to be approximately 30% if routine laparotomy is performed in all penetrat­ing ...
Harin H Modi, Vikas H Janu, Gulabbhai R Patel   +2 more
doaj  

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

Hydrocortisone therapy for patients with septic shock [PDF]

, 2008
Background Hydrocortisone is widely used in patients with septic shock even though a survival benefit has been reported only in patients who remained hypotensive after fluid and vasopressor resuscitation and whose plasma cortisol levels did not rise ...
Sprung, Charles L, Sprung, Charles L., Benbenishy, Julie, Briegel, Josef, Kalenka, Armin, Freivogel, Klaus, Payen, Didier, Reinhart, Konrad, Forst, Helmuth, Annane, Djillali, Singer, Mervyn, Benbenishty, Julie, Moreno, Rui, Weiss, Yoram G, Laterre, Pierre-Francois, Cuthbertson, Brian, Keh, Didier, Cuthbertson, Brian H, Weiss, Yoram G., CORTICUS Study Group   +19 more
core   +1 more source

Introducción del colgajo de epiplón en el tratamiento de las mediastinitis aguda en el Cardiocentro de Santiago de Cuba Introduction of the omentum flap into the treatment of acute mediastinitis at the Heart Center of Santiago de Cuba

Medisan, 2011
La esternotomía media es la vía de acceso más frecuentemente utilizada en la cirugía cardiovascular, lo cual convierte a la mediastinitis en una complicación no tan frecuente como peligrosa para la vida del paciente. A tales efectos se realizó un estudio
Jorge Carlos Machín Rodríguez, José Manuel Castillo Martínez, Juan Oscar Martínez Muñiz, Fredy Eladio Torralbas Reverón, Frank Josué Perdomo García   +4 more
doaj  

Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant Recipients

Case Reports in Transplantation, 2019
Surgical site infections (SSI) of the abdominal wall in renal transplant recipients can on occasion require management with negative pressure wound therapy (NPWT). This is often successful, with a low risk of further complications.
Susanna Lam, Ngee-Soon Lau, Jerome Martin Laurence, Deborah Jean Verran   +3 more
doaj   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

Advanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang, Jiadong Yu, Guolin Li, Ya Li, Fanlian Zeng, Jing Hu, Yifan Zhou, Chengcheng Yue, Qixiang Zhao, Chen Zhang, Hong Zhou, Fulei Zhao, Yawen Hu, Pei Zhou, Linna Gu, Yuting Feng, Mingxiang He, Shishi Huang, Xiaochi Sun, Xinmeng Wang, Jie Tang, Xinyu Zeng, Wenling Wu, Nongyu Huang, Xinai Cui, Kaijun Cui, Jiong Li   +26 more
wiley   +1 more source

Wound healing and skin in severe sepsis [PDF]

, 2016
It is a generally accepted dogma that sepsis disturbs skin function and wound healing, but surprisingly there is only remote pathophysiological evidence available behind that presumption. As the skin is the largest defensive barrier, the skin dysfunction
Koskela, M. (Marjo)
core  

Risk Assessment of Gram-Negative Sepsis in Cardiac Surgery: From Clinical and Anamnestic Predictors to a Prognostic Model

Український журнал серцево-судинної хірургії
Gram-negative sepsis remains a serious threat to cardiac surgery patients. The incidence of gram-negative sepsis at the preoperative stage accounts for 10-25 % of all reported cases.
Kostiantyn P. Chyzh, Hanna B. Koltunova, Andriy.P. Mazur, Mikhailo Yu. Antomonov, Nataliia M. Verych   +4 more
doaj   +1 more source

Source of Pseudomonas Aeruginosa in Burn Wound

Indian Journal of Plastic Surgery, 1978
1. Ps. aerug. is the commonest causative organism of burn wound sepsis. In our patients i. e. 23 out of 35 patients it was present either alone or in combination.
R. K. Keswani, R. S. Hooda, S. N. Behl, G. L. Naryana, T. D. Chugh   +4 more
doaj   +1 more source