Results 41 to 50 of about 819,049 (308)

Surgical Validation of High-Resolution Ultrasonography in Detection of Missed Tendon and Nerve Injuries after Penetrating Wounds of Hand and Wrist

open access: yesTurkish Journal of Plastic Surgery, 2020
Background: To surgically validate high-resolution ultrasonography (USG) in the detection of missed tendon and nerve injuries after penetrating wounds of the hand and wrist.
Mohd Altaf Mir   +3 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

War injuries of the blood vessels of the extremities [PDF]

open access: yesVojnosanitetski Pregled, 2002
Treatment results of 200 injured with the lesions of 282 magisterial blood vessels were analyzed. All were combat injuries, and the majority was caused by the fragments of explosive device.
Radulović Svetozar   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

APPENDICULAR CARCINOID IN A VICTIM WITH SIMULTANEOUS CHEST AND ABDOMEN TRAUMA

open access: yesНеотложная медицинская помощь, 2017
The article reports a clinical case of surgical therapy of a patient with simultaneous chest and abdomen trauma and carcinoid of the appendix.
E. V. Tatarinova, G. A. Nefedova
doaj   +1 more source

Comparison of Penetrating and Blunt Traumatic Diaphragmatic Injuries [PDF]

open access: yesJournal of Trauma and Injury, 2019
Purpose Traumatic diaphragmatic injury (TDI) is no longer considered to be a rare condition in Korea. This study investigated differences in the prevalence of accompanying injuries and the prognosis in patients with traumatic diaphragmatic damage ...
Sang Su Lee   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Performance of pre-hospital evaluations in ruling out invasive chest stab wounds

open access: yesScandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2020
Background Some guidelines advocate for managing patients with penetrating thoracic wounds in trauma centres with cardiothoracic surgery. This systematic approach is questionable. Only 15% of these patients require surgery.
Pascal Augustin   +7 more
doaj   +1 more source

Primary vitrectomy in total and subtotal hemophthalmos of traumatic etiology

open access: yesРоссийский офтальмологический журнал, 2023
Purpose: to present the functional results of primary early vitrectomy in patients with subtotal and total hemophthalmos with penetrating wounds and severe contusions of the eye. Material and methods.
S. N. Subbotina   +2 more
doaj   +1 more source

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