Results 41 to 50 of about 22,877 (311)

PENETRATING WOUND OF THE LUNG [PDF]

open access: yesJournal of the American Medical Association, 1909
The following case is of interest, not only on account of its very extensive character, but also as it illustrates a type of wound that has become extremely rare since men have discarded the spear in battle. History of Accident. —The patient was a tall, well-muscled negro, 20 years of age, engaged in saw-mill work. On June 22, 1908, about 10:30 a. m.,
openaire   +2 more sources

Aseptic tissue necrosis and chronic inflammation after irrigation of penetrating hand wounds using Octenisept®

open access: yes, 2011
Penetrating hand wounds are common and these are managed by thorough debridement. However, stab wounds without evidence of divided structures are often treated with irrigation using antiseptic substances, antibiotic therapy, and immobilization ...
E. Vögelin   +3 more
core   +1 more source

Diagnostic problems and emergency cardiac surgery in cut-like penetrating cardiac trauma

open access: yes, 2021
Penetrating cardiothoracic injuries have occurred in large numbers throughout the world from ancient times to the present. A small percentage of them, but the most severe, are penetrating cardiac traumas.
Bartuś, Krzysztof   +11 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Subcutaneous and visceral fat are associated with worse outcomes in gunshot injuries but not stab injuries to the torso

open access: yesTrauma Surgery & Acute Care Open, 2023
Purpose The effect of obesity in penetrating trauma outcomes is poorly understood. The purpose of this study was to determine if there is a protective effect of subcutaneous or visceral fat from stab and gunshot wounds.Methods 443 patients admitted after
Christopher Mejias   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Backbone and a spinal cord gunshot wounds in the peace time

open access: yesUkrainian Neurosurgical Journal, 2006
The group of 120 injured patients with backbone and a spinal cord gunshot wounds in a peace time were investigated. Their characteristic features were revealed depending on age, weapon kinds and injury level.
V. V. Mogila, S. V. Kurteev
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Surgical Validation of High-Resolution Ultrasonography in Detection of Missed Tendon and Nerve Injuries after Penetrating Wounds of Hand and Wrist

open access: yesTurkish Journal of Plastic Surgery, 2020
Background: To surgically validate high-resolution ultrasonography (USG) in the detection of missed tendon and nerve injuries after penetrating wounds of the hand and wrist.
Mohd Altaf Mir   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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