Results 51 to 60 of about 22,877 (311)

Avaliação da incidência de laparotomias não terapêuticas nos pacientes vítimas de ferimentos abdominais por arma de fogo ou arma branca no Hospital Florianópolis [PDF]

open access: yes, 2004
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Froehner, Camila Duarte
core  

Simultaneous penetrating wounds of the myocardium and aorta caused by firearms: surgical treatment.

open access: yes, 1979
The frequency of trauma and penetrating wounds ofthe heart and the great intrathoracic vessels is continuouslyincreasing. In peacetime heart wounds constituteabout 3% of all penetrating wounds of thechest.
Bondioli, A   +13 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

APPENDICULAR CARCINOID IN A VICTIM WITH SIMULTANEOUS CHEST AND ABDOMEN TRAUMA

open access: yesНеотложная медицинская помощь, 2017
The article reports a clinical case of surgical therapy of a patient with simultaneous chest and abdomen trauma and carcinoid of the appendix.
E. V. Tatarinova, G. A. Nefedova
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Performance of pre-hospital evaluations in ruling out invasive chest stab wounds

open access: yesScandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2020
Background Some guidelines advocate for managing patients with penetrating thoracic wounds in trauma centres with cardiothoracic surgery. This systematic approach is questionable. Only 15% of these patients require surgery.
Pascal Augustin   +7 more
doaj   +1 more source

Primary vitrectomy in total and subtotal hemophthalmos of traumatic etiology

open access: yesРоссийский офтальмологический журнал, 2023
Purpose: to present the functional results of primary early vitrectomy in patients with subtotal and total hemophthalmos with penetrating wounds and severe contusions of the eye. Material and methods.
S. N. Subbotina   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Sharp penetrating wounds: spectrum of imaging findings and legal aspects in the emergency setting

open access: yes, 2015
The main cause of severe civilian trauma is not the same all over the world; while in Europe the majority of cases are due to blunt traumatic injury, in the United States, penetrating gunshot wounds are the most common.
Russo, Anna   +18 more
core   +1 more source

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