Results 91 to 100 of about 992,812 (310)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Quantitative Assessment of Angiogenesis in Skin Wound Healing by Multi-Optical Imaging Techniques [PDF]

, 2022
Lishuang Li, Yanan Sun, Honghui He, Gaiying He, Shuhua Ma, Weifeng Yang, Yi Wang   +6 more
openalex   +1 more source

Hydrogel-Based Strategies to Advance Therapies for Chronic Skin Wounds.

Annual Review of Biomedical Engineering, 2019
Chronic skin wounds are the leading cause of nontraumatic foot amputations worldwide and present a significant risk of morbidity and mortality due to the lack of efficient therapies.
L. D. da Silva, R. Reis, V. Correlo, A. P. Marques   +3 more
semanticscholar   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Assessment of applicability of Ganga Hospital Score in the management of open tibia fracture

Bone & Joint Open
Aims: Open fractures of the tibia encompass a wide spectrum of injuries, posing multiple challenges for treating surgeons. This study evaluates the Ganga Hospital Open Injury Severity Score (GHOISS) in predicting the outcomes of open tibia fractures in ...
Innocent Kwizera, Jean C. Byiringiro, J. C. A. Ingabire, Emmanuel Murwanashyaka, Jean L. Mwizerwa   +4 more
doaj   +1 more source

Systematic Review of Stem-Cell-Based Therapy of Burn Wounds: Lessons Learned from Animal and Clinical Studies [PDF]

, 2020
Josefine Lin Henriksen, Nana Brandborg Sørensen, Trine Fink, Vladimir Zachar, Simone Riis Porsborg   +4 more
openalex   +1 more source

The Synergistic Effect of Electrical Stimulation and Dermal Fibroblast Cells-Laden 3D Conductive Hydrogel for Full-Thickness Wound Healing [PDF]

, 2023
Yen-Hong Lin, En‐Wei Liu, Yun-Jhen Lin, Hooi Yee Ng, Jian‐Jr Lee, Tuan-Ti Hsu   +5 more
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Botulinum toxin in wound treatment – literature review

Journal of Education, Health and Sport
Introduction and purpose Botulinum toxin has been used in medicine since the 1970s, although many years earlier it was known only as a biological weapon. Originally, it was used in medicine to treat strabismus in children.
Aneta Jerzak, Aleksandra Janocha, Anna Hitnarowicz, Bożena Kmak, Anna Szot, Agnieszka Pociecha   +5 more
doaj   +1 more source

Combination of Beta Glucan, Honey and Chlorhexidine in the Wound Management in a Cat a Case Report

Folia Veterinaria, 2019
Wound management is one of the oldest and one of the most frequent therapeutic activities in medicine. Over the centuries there has been described and tested many therapeutic substances for the treatment of wounds with various effects.
Micháľová A., Micháľ M., Fialkovičová M.   +2 more
doaj   +1 more source