Results 71 to 80 of about 814,933 (365)
International Journal of Nursing Studies AdvancesBackground: Chronic wounds place a substantial clinical and economic burden on health systems and significantly reduce the quality of life of those affected.
Miguel Ángel Díaz-Herrera +11 more
doaj +1 more source
An audit to determine the clinical effectiveness of a pathway for managing wound infection [PDF]
, 2015 Prevention of wound infection is a key objective in the planning of care for patients with wounds. The potential for wound infection, particularly in chronic wounds that are heavily contaminated with bacteria, can be high (Bowler et al, 2001).
Grothier, Lorraine, Stephenson, John
core
Management of Forehead Scars [PDF]
, 2017 This article provides an overview of scar management within the forehead region. It addresses the unique challenges specific to the treatment of forehead wounds. A logical, stepwise approach is used.
Bryant, Lucas M. +2 more
core +2 more sources
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Chronic Wounds: The Persistent Infection Problem [PDF]
, 2013 Chronic wounds heal poorly and can have a huge impact on a sufferer’s life. They are caused by a number of factors, one of which is the presence of persistent infections.
Davis, NG
core
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Resistance of Scotch Pine Varieties to Zimmerman Pine Moth (Lepidoptera: Pyralidae) and Its Impact on Sales in a Choose and Cut Christmas Tree Plantation [PDF]
, 2017 Nine varieties of Scotch pine, Pinus sylvestris, were assessed for their susceptibility to Zimmerman pine moth, Dioryctria zimmermani, in a choose and cut Christmas tree plantation.
Sadof, Clifford S
core +3 more sources
Protein kinase FAM20C—when subcellular localization matters
FEBS Letters, EarlyView.FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source
Management of radiation wounds
Indian Journal of Plastic Surgery, 2012 Radiotherapy forms an integral part in cancer treatment today. It is used alone or in combination with surgery and chemotherapy. Although radiotherapy is useful to effect tumour death, it also exerts a deleterious effect on surrounding normal tissues ...
Subramania Iyer, Deepak Balasubramanian
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source