Results 101 to 110 of about 183,635 (306)

Possible male infanticide in wild orangutans and a re-evaluation of infanticide risk [PDF]

open access: yes, 2019
Infanticide as a male reproductive tactic is widespread across mammals, and is particularly prevalent in catarrhine primates. While it has never been observed in wild orangutans, infanticide by non-sire males has been predicted to occur due to their ...
Knott, Cheryl D.   +6 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Evaluating the Relationship between Rib Fractures and the Probability of Abdominal Trauma; a Brief Report

open access: yesطب اورژانس ایران, 2015
Introduction: Trauma is one of the most important causes of death in patients under 40 years of age and the third common cause of death regardless of age. Rib cage damages are one of the major reasons for death in the early minutes post-trauma. Therefore,
Vahid Monsef Kasmaei   +3 more
doaj  

Increased serum levels of procollagen type III peptide in severely injured patients [PDF]

open access: yes, 1993
Objectives: To determine the serum concentrations of procollagen type in peptide in severely injured patients with different outcomes and to evaluate the relationship between serum procollagen type III peptide concentrations, sources of increased ...
Duswald, Karl-Heimo   +6 more
core  

Societal consequences of falls in the older population: Injuries, healthcare costs, and long-term reduced quality of life [PDF]

open access: yes, 2011
BACKGROUND:: Fall incidents are a major cause of morbidity and mortality in older adults. The aim of this cohort study was to determine the incidence, costs, and quality of life for fall-related injuries in the older Dutch population presenting at the ...
Dolan   +21 more
core   +3 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Human Papillomavirus infection in oral and anogenital sites

open access: yesDST, 2021
 Introduction: HPV infection causes cancer at several anatomical sites. However, the infection’s natural history in non-cervical sites is understudied.
Thaissa Isaias Cordeiro   +7 more
doaj  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Medical Care of American POWs during the War of 1812 [PDF]

open access: yes, 2012
In 2005, a service in Halifax commemorated US soldiers and sailors who perished in Britain’s Melville Island prisoner-of-war camp during the War of 1812 and whose remains now lie on Deadman’s Island, a nearby peninusla.
Newfield, Gareth A.
core   +1 more source

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