Results 81 to 90 of about 89,517 (245)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Theoretical model and conceptual frameworks of pressure injuries and other chronic wounds. History and development

, 2022
El presente artículo hace un repaso histórico por los marcos conceptuales sobre las lesiones por presión y otros tipos de heridas crónicas. En esta revisión se presentan 4 de los modelos más influyentes y representativos de las últimas décadas: a) el ...
Pancorbo Hidalgo, Pedro Luis, Soldevilla Agreda, J. Javier, Verdú, José, Rodríguez Palma, Manuel, García Fernández, Francisco Pedro   +4 more
core  

Outcomes and costs of penetrating trauma injury in England and Wales [PDF]

, 2008
The official published version of the article can be found at the link below.Background: Penetrating trauma injury is generally associated with higher short-term mortality than blunt trauma, and results in substantial societal costs given the young age ...
Morris, S, Nielsen, TG, Ridley, S, Christensen, MC, Lecky, FE   +4 more
core   +1 more source

Reconstruction of soft-tissue lesions of the foot with the use of the medial plantar flap

Revista Brasileira de Ortopedia
OBJECTIVE: To study use of the medial plantar flap for reconstruction of the heel and foot. METHOD: The authors share their clinical experience with the use of the medial plantar artery flap for coverage of tissue defects around the foot and heel ...
Jefferson Lessa Soares de Macedo, Simone Corrêa Rosa, Altino Vieira de Rezende Filho Neto, Adilson Alves da Silva, Alex Corcino Silva de Amorim   +4 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

The financial burden of chronic wounds in primary care: A real-world data analysis on cost and prevalence [PDF]

Background. Chronic wounds place a substantial clinical and economic burden on health systems and significantly reduce the quality of life of those affected.
Rodríguez Martínez, Francisco Javier, Díaz-Herrera, Miguel Ángel, Verdú, José, Acedo-Anta, Mateo, Tujillo-Flores, Gema, Cunillera-Puértolas, Oriol, Martínez-Riera, José Ramón, Almeda Ortega, Jesús, Gea Caballero, Vicente, Tuset Mateu, Nuria, Martínez Riera, José Ramón, Acedo-Anta, Mateo [0000-0003-4512-2696], González Duran, Mónica, González-Durán, Mónica, Verdú Soriano, José, Tuset-Mateu, Nuria, Cunillera Puértolas, Oriol, Tujillo Flores, Gema, Sanllorente-Melenchón, Albert, Verdú-Soriano, Jose [0000-0002-8307-7323], Almeda-Ortega, Jesús, Díaz-Herrera, Miguel Ángel [0000-0001-6014-2180], Martínez-Riera, José Ramón [0000-0002-4926-6622], Sanllorente Melenchon, Albert, Rodríguez-Martínez, Francisco Javier, Acedo, Mateo, Gea-Caballero, Vicente, Gea Caballero, Vicente Antonio, Díaz Herrera, Miguel Ángel, Cunillera-Puértolas, Oriol [0000-0003-2891-099X]   +29 more
core   +1 more source

Long-Term Traumatic and Asymptomatic Aorto-Right Atrial Fistula

Brazilian Journal of Cardiovascular Surgery
Aorto-atrial fistulas due to cardiac trauma are rare, and survivors require immediate surgical correction. Here, we report a case of an aorto-right atrial fistula due to penetrating trauma after a 16-year evolution, which developed symptoms of acute ...
Sandro Gonçalves de Lima, Andréa Bezerra de Melo da Silveira Lordsleem, Kaique Leal Campos, Juliana Guedes Silva, Marcelo Antônio Oliveira Santos, Brivaldo Markman Filho   +5 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

The endovascular treatment of traumatic cranio-cervical vascular injuries [PDF]

, 2013
Includes abstract.
Ssenyonga, Peter Kato
core   +1 more source