Results 61 to 70 of about 89,517 (245)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Revista do Colégio Brasileiro de CirurgiõesOBJETIVO: avaliar os aspectos epidemiológicos e fatores prognósticos associados a uma série de pacientes vítimas de traumatismo cranioencefálico por projétil de arma de fogo (PAF). MÉTODOS: Foram revisados os prontuários de 181 pacientes da Disciplina de
Rodrigo Becco de Souza +4 more
doaj +1 more source
Trauma vascular en extremidades: enfoque diagnóstico y terapéutico en urgencias
Medicina U.P.B., 2019 El trauma vascular en las extremidades es una causa importante de mortalidad y morbilidad. Por su fisiopatología se conoce que esta lesión puede tener efectos sistémicos ocasionados por el choque hemorrágico, y efectos locales debido a la isquemia ...
Johanna Caicedo Valle +2 more
doaj +1 more source
Acute Acalculous Cholecystitis in Severe Trauma Patients: A Single Center Experience [PDF]
Journal of Acute Care Surgery, 2015 Purpose: Early diagnosis and prompt treatment of acute acalculous cholecystitis is important, because it is associated with high mortality. In major trauma patients, besides the direct damage the trauma itself causes, many complications can occur due to ...
Jong Beom Kim +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Epidemiological review of paediatric firearm injuries and mortalities in Cape Town [PDF]
, 2013 Includes abstract.
Sammour, Shadi
core +1 more source
USE OF SPATIOTEMPORAL GAIT PARAMETERS TO DETERMINE RETURN TO SPORTS AFTER ACL RECONSTRUCTION [PDF]
Acta Ortopédica Brasileira, 2016 Objective : To compare gait spatiotemporal parameters of healthy and ACL reconstructed subjects in order to classify the status of gait normality. Methods : Fourteen healthy subjects and eight patients submitted to ACL reconstruction walked along a ...
GUSTAVO LEPORACE +7 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
BioImpacts, 2012 Introduction: Emergency department manages several kinds of wounds including simple, non-bite traumatic wounds and lacerations. Prophylactic antibiotic therapy is one of prescribed treatment in these conditions.
Barzin Bagheri-Behzad +5 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source