Results 71 to 80 of about 89,517 (245)

Spine Injuries Are Common Among Asymptomatic Patients After Gunshot Wounds

, 2005
BACKGROUND:Spine injuries after gunshot wounds are thought to be rare among asymptomatic patients. The occurrence of spine injuries among asymptomatic patients with gunshot wounds was studied to determine the necessity for mandatory spine immobilization ...
Soffer, Dror, Shaw, Christiana, Hasharoni, Amir, Lynn, Mauricio, Klein, Yoram, Cohn, Stephen   +5 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Geriatric Injuries among Patients Attending a Regional Hospital in Shinyanga Tanzania [PDF]

, 2012
Geriatric injuries pose a major challenge to surgeons and general practitioners in developing countries. The objective of this study was to determine the prevalence, injury characteristics and outcomes of geriatric injury among patients at Shinyanga ...
Mbelenge, Nkinda, Ngayomela, Isdor H., Mchembe, Mabula, Gilyoma, Japhet M., Ngayomela, Isidori H., Mabula, Joseph B., Chalya, Phillipo L., Dass, Ramesh M., Ngallaba, Sospatro E.   +8 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Prevalence of traumatic brain injury amongst children admitted to hospital in one health district : a population-based study [PDF]

There is a dearth of information regarding the prevalence of brain injury, serious enough to require hospital admission, amongst children in the United Kingdom.
Magnay, Andrew R., Hawley, Carol, Ward, Anthony B., Long, Julie, Owen, David   +4 more
core   +1 more source

A Retrospective Study of Geriatric Trauma at a Large Teaching Hospital After the 2008 Wenchuan Earthquake

International Journal of Gerontology, 2010
Background: On May 12, 2008, a large earthquake measuring 8.0 on the Richter scale struck Wenchuan County, Sichuan Province, China. To date, there has been no report specifically addressing the clinical features of traumatized geriatric patients in the ...
Jin Wen, Chen-Lu Yang, Ying-Kang Shi, You-Ping Li, Yu-Lin Ji, Jin Liu   +5 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Treatment of acute wounds and injuries : cuts, bites, bruises and sprains [PDF]

, 2022
Acute wounds and injuries are a common daily occurrence, and their appropriate care is critical to healing. In South Africa, community pharmacists are often the first to encounter acute wounds and injuries such as cuts, bites, bruises and sprains, due ...
Mlambo, Shamiso Shelter, Parkar, Hafiza, Naude, L., Cromarty, Allan Duncan   +3 more
core   +1 more source

COMPARISON OF STANDARD NEGATIVE PRESSURE WOUND THERAPY ALONG WITH NEGATIVE PRESSURE WOUND THERAPY PLUS INSTILLATION OF NORMAL SALINE IN ACUTE TRAUMATIC WOUNDS

Pakistan Armed Forces Medical Journal, 2019
Objective: To compare the efficacy of standard negative pressure wound therapy with combination of negative pressure wound therapy (NPWT) and instillation of normal saline (NS) in acute traumatic wounds. Study Design: Randomized controlled trial.
Asad Maqbool, Muhammad Rizwan Aslam, Rao Saood Ahmed, Humza Mumtaz, Syed Iftikhar Ali, Usama Bin Zubair   +5 more
doaj