Results 31 to 40 of about 76,979 (255)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Profile of thoracic trauma victims submitted to chest drainage

Revista do Colégio Brasileiro de Cirurgiões
Objective: to describe and compare the variables involved in trauma victims undergoing thoracic drainage. Methods: we conducted a retrospective, analytical, descriptive, cross-sectional study, with medical records of patients attended at the Trauma ...
CESAR AUGUSTO BROSKA JÚNIOR, ADRIANE BARBOSA BOTELHO, ANDRÉ DE CASTRO LINHARES, MARIANA SANTOS DE-OLIVERIA, GABRIELA VERONESE, CARLOS ROBERTO NAUFEL JÚNIOR, LISLAINE CRUZ BATISTA, MARIA ANGÉLICA KURPEL DIOGO   +7 more
doaj   +1 more source

Removal of a melee weapon forgotten in the orbital cavity: case report

RGO: Revista Gaúcha de Odontologia, 2020
Facial aggressions perpetrated with melee weapons cause injuries that are difficult to treat. Possible aesthetic-functional sequels can cause irreparable damage to the patients.
Mário Serra FERREIRA, Jamil Elias DIB, Matheus Branco Elias DIB, Ricardo Guimarães NEVES, Maria Alves Garcia Santos SILVA   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Adherence to national trauma triage criteria in Norway: a cross-sectional study

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background Norwegian hospitals employed individual trauma triage criteria until 2015 when nationwide criteria were implemented. There is a lack of empirical evidence regarding adherence to Norwegian national criteria for activation of the trauma team ...
Einar Frigstad Hoås, Waleed Mohammed Majeed, Olav Røise, Oddvar Uleberg   +3 more
doaj   +1 more source

Trauma hepático: epidemiologia de cinco anos em um serviço de emergência

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: analisar características epidemiológicas relacionadas ao trauma hepático e fazer breve revisão das modalidades diagnósticas e de tratamento.
Carla Martinez Menini Stalhschmidt, Beatriz Formighieri, Débora Majszak Marcon, Aline Luri Takejima, Luis Guilherme Sanches Soares   +4 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

A Case Report of Treatment of a Wound with Extensive Skin Necrosis Using Modern Dressing in a One-Month-Old Infant

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2019
Background and Objectives: A wound is an injury or rupture on the surface of skin, which is caused physically, chemically, mechanically, or by heat.   Case Report: The patient was a one-month-old infant who admitted to the hospital with seizure.
Robabeh Ahmadli, Narges Farshadpour, Zahra Kaffash   +2 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source