Results 61 to 70 of about 14,946 (248)

Fiber comb filters based on UV-writing Bragg gratings in graded-index multimode fibers

open access: yesOptics Express, 2005
We report a new kind of comb filters based on fiber Bragg gratings in graded-index multimode fibers. It produces two groups of spectra with a total of 36 reflection peaks that correspond to 18 principal modes and cross coupled modes. The mode indices and wavelength spacings have been investigated theoretically and experimentally.
Yu, Liu, John, Lit, Xijia, Gu, Li, Wei
openaire   +2 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

A Linux Kernel USB Proxy With Integrated Threat Detection

open access: yesIEEE Access
Universal Serial Bus (USB) devices are widely used due to their flexibility, but they also introduce security risks because they expose multiple interfaces that are implicitly trusted by the operating system.
Madalin Vasile, Mariana Mocanu
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Exposure to English Linguistic Environment, Affective Filters and the Writing Competence of Students

open access: yesUIC Research Journal, 2016
<p>This descriptive-correlation study aimed to determine the influence of exposure to the English linguistic environment and affective filters on the writing competence of 176 students enrolled in English Proficiency Program (EPP) classes of a college in Davao in the school year 2011-2012.
openaire   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

INTELLIGENT WRITING ANALYSIS SYSTEM BASED ON TOUCH TRAJECTORIES AND SPLINE FILTERING

open access: yesВестник КазУТБ
The article presents the development of an intelligent writing analysis system based on touch trajectories and spline filtering methods, focused on the diagnosis and development of graphomotor skills in preschoolers in digital writing learning. The relevance of the study is due to the need for early detection of difficulties in the formation of ...
A. Shaporeva   +7 more
openaire   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

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