Results 51 to 60 of about 613,967 (285)
Improved Collaborative Filtering Automatic Assessment System for Teaching English Writing in College
Advances in Multimedia, 2022 In the context of economic globalization, as an international language, English plays an increasingly essential role in the communication and exchange of ideas. As an output skill that fully reflects one’s linguistic and cultural literacy and logical thinking ability, English writing is undoubtedly the most difficult of the four basic skills of ...
openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Bioinformatics and Biology InsightsDifferential gene expression analysis of RNA Sequencing (RNA-Seq) data is crucial for understanding key patterns of gene regulation and enhancing our knowledge of biological processes and diseases. The workflow of this analysis comprises quality control,
Sanae Esskhayry +7 more
doaj +1 more source
, 2021 Write Reason is a tool for planning and writing documents. In the left pane is a text editor. In the right pane is a free-form mapping interface.
Miguel A. Nacenta +2 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Applied SciencesThe Bi-directional Evolutionary Structural Optimization (BESO) method, owing to its algorithmic simplicity and strong scalability, has emerged as one of the most prevalent topology optimization methodologies in current research and industrial ...
Dong Sun, Xudong Yang, Hui Liu, Hai Yang
doaj +1 more source
Italiano LinguaDue, 2018 Il contributo ha lo scopo di fornire indicazioni sul metodo di lavoro seguito da Raffaello Fornaciari nel compendiare e adattare la sua celebre e innovativa Sintassi italiana dell’uso moderno (1881) per approdare alla Sintassi per le scuole dell’anno ...
Alessio Ricci
doaj +1 more source
Femtosecond direct laser writing of photonic spatial filters in soda–lime glass
Lithuanian Journal of Physics, 2015 An experimental study of the efficiency of recently predicted photonic crystal (PhC) based spatial filtering is provided. Photonic structures are fabricated using a direct laser writing technique employing point-by-point modification by tightly focused femtosecond pulses in soda–lime glass.
Darius Gailevičius +6 more
openaire +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source