Results 71 to 80 of about 613,967 (285)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Exposure to English Linguistic Environment, Affective Filters and the Writing Competence of Students

open access: yesUIC Research Journal, 2016
<p>This descriptive-correlation study aimed to determine the influence of exposure to the English linguistic environment and affective filters on the writing competence of 176 students enrolled in English Proficiency Program (EPP) classes of a college in Davao in the school year 2011-2012.
openaire   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Fiber comb filters based on UV-writing Bragg gratings in graded-index multimode fibers

open access: yesOptics Express, 2005
We report a new kind of comb filters based on fiber Bragg gratings in graded-index multimode fibers. It produces two groups of spectra with a total of 36 reflection peaks that correspond to 18 principal modes and cross coupled modes. The mode indices and wavelength spacings have been investigated theoretically and experimentally.
Yu, Liu, John, Lit, Xijia, Gu, Li, Wei
openaire   +2 more sources

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A Linux Kernel USB Proxy With Integrated Threat Detection

open access: yesIEEE Access
Universal Serial Bus (USB) devices are widely used due to their flexibility, but they also introduce security risks because they expose multiple interfaces that are implicitly trusted by the operating system.
Madalin Vasile, Mariana Mocanu
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Investigating the memory requirements for publish/subscribe filtering algorithms [PDF]

open access: yes, 2005
Various filtering algorithms for publish/subscribe systems have been proposed. One distinguishing characteristic is their internal representation of Boolean subscriptions: They either require conversions to disjunctive normal forms (canonical approaches)
Bittner, Sven, Hinze, Annika
core  

Escritura colectiva como resistencia : el colectivo "Write like a girl" [PDF]

open access: yes, 2021
"Write like a girl", parafraseo del ya clásico "Fight like a girl", anónimo y popular, acuñado por las feministas para dar a entender que las chicas también saben pelear. Sin embargo, no podemos dejar de preguntarnos: ¿qué sería hacer
Colectivo “Write like a girl"
core  

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