TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Exploring writhe in supercoiled minicircle DNA [PDF]
Using λ-Int recombination in E. coli, we have generated milligram quantities of supercoiled minicircle DNA. Intramolecular Int recombination was efficient down to lengths ~254 bp. When nicked and religated in the presence of ethidium bromide, 339 bp minicircles adopted at least seven unique topoisomers that presumably correspond to ΔLk ranging from 0 ...
Jonathan M, Fogg +6 more
openaire +2 more sources
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source
Two centuries from the birth of Petar II Petrović Njegoš (Neboš of the Serbian romanticism) [PDF]
Petar II Petrović Njegoš (1813 - 1851) was a successful ruler, bishop, and writer at the same time. He maintained the independence of Montenegro surrounded by the enemies: Turks (Herzegovinian Ali-pasha Rizvanbegović, and Osman-pasha Skadarski ...
Lazarević Velibor
doaj
Study the antinociceptive effect of the Zingiber officinale ethanolic extract and Vitamin C in rats
The present study was designed to investigate the antinociceptive activity of seperate and combined treatments of ethanol extract of Zingiber officinale rhizomes and vitamin C on visceral nociception induced by intraperitoneal injection of 2% acetic acid
Wisam. H. S. AL- Shebani
doaj +1 more source
The distribution of writhe for a representative sample of >10000 proteins from the PDB in black.
In blue we see the theoretical writhe bound [33] with R = 2.7. In green, we see linear growth in writhe with a gradient of 0.12. Inset: A: PDB entry 1VQ3. B: PDB entry 2OMZ. C: PDB entry 2RH3. D: PDB entry 4O4B.
Arron Bale (17458357) +2 more
core +1 more source
Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle +4 more
wiley +1 more source
An example of the potential domains present in a complex entangled yet net zero writhe structure.
An example of the potential domains present in a complex entangled yet net zero writhe structure.
Arron Bale (17458357) +2 more
core +1 more source

