Results 121 to 130 of about 3,900,680 (304)
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Independent, imaginative writing: lots of problems and some solutions [PDF]
This chapter describes part of a series of curriculum development projects set up to identify and tackle the difficulties of teaching imaginative story writing to children aged 7-12 years.
Ellis, Sue
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
IMPROVING STUDENTS` ABILITY IN WRITING RECOUNT TEXT THROUGH STORYBOARD LEARNING TECHNIQUE AT THE EIGHTH GRADE STUDENTS OF SMP NU KARANGAMPEL (Classroom Action Research ) [PDF]
Siti Paridah (14111310067) Improving Students` Ability in Writing Recount Text Through Storyboard Learning Technique at the Eighth Grade Students of SMP NU Karangampel (Classroom Action Research). The students` ability in writing recount text is still
SITI PARIDAH,
core
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Whys and hows of in-house writing [PDF]
The combining of requisite technical knowledge with requisite writing ability is addressed. Considerations in the development of in-house writing courses, in-plant training, are presented and evaluated.
Lane, J. C.
core +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
TEACHING THEME AND THEMATIC PROGRESSION TO TOURISM STUDENTS AND ITS IMPLICATIONS ON THEIR WRITINGS [PDF]
Teaching writing to tourism students is challenging. Many students of diploma programs in hotel and tourism tend to focus to building practical skills such as cooking techniques or cutting methods, setting up table for lunch or dinner, or how to handle
Sopian, Tatang
core
THINK TALK WRITE STRATEGY ON STUDENTS’ WRITING ABILITY
: Speaking skills are skills that enable us to communicate effectively. This skill has the most important goal for student success, especially for class XI of SMA because they will face the era of globalization in the world. As for the problems faced by class XI students of SMA Darus Su'ada Al-Ahad, most of them are not able to speak English.
openaire +1 more source

