Results 131 to 140 of about 1,028,172 (298)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Methods for Evaluating Educational Programs – Does Writing Center Participation Affect Student Achievement? [PDF]

This paper evaluates the eff ectiveness of the introduction of a Writing Center at a university. The center has the purpose to provide subject-specifi c courses that aim to improve students‘ abilities of scientifi c writing.
Carsten J. Crede, Julia Bredtmann, Sebastian Otten   +2 more
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Pengaruh Implementasi Asesmen Portofolio Terhadap Kemampuan Menulis Dalam Bahasa Inggris Ditinjau Dari Motivasi Berprestasi Siswa Kelas XI Man Amlapura [PDF]

, 2013
PENGARUH IMPLEMENTASI ASESMEN PORTOFOLIO TERHADAP KEMAMPUAN MENULIS DALAM BAHASA INGGRIS DITINJAU DARI MOTIVASI BERPRESTASI SISWA KELAS XI MAN AMLAPURA Lestari Budi Utami1, I Made Yudana2, A. A. I. N.
Marhaeni, M. P. (MA), UTAMI, L. B. (LESTARI), Yudana, M. P. (M)   +2 more
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The Impact of Reflective Writing on Writing Achievement, Vocabulary Achievement and Critical Thinking of Intermediate EFL Learners

Journal of Studies in Education, 2015
<p>The present study investigated the effectiveness of a rather newly- developed method in language teaching that was reflective writing in improving EFL learners’ writing achievement, vocabulary achievement and critical thinking. To fulfill the purpose of the study, first 60 participants from among 100 intermediate learners studying at Tehran ...
openaire   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Improving the Quality of Teaching Learning Process of Writing Class Through Lesson Study [PDF]

, 2015
Lesson Study (LS) is a professional development process that Japanese teachers engage into systematicallyexamine their practice, with the goal of becoming more effective. In the application teachers or lecturers mustalways improve the quality of teaching
Mariana, L. -. (Lina), Nurhajati, D. (Diani)   +1 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

The Effect of Communicative Language Teaching on the Students\u27 Achievement in Writing Hortatory [PDF]

, 2014
This study deals with the effect of Communicative Language Teaching on the students\u27 achievement in writing hortatory. The objective of this study is to find out whether Communicative Language Teaching significantly affects students\u27 achievement ...
Husein, R. -. (Rahmad), Tarigan, F. N. (Fatin)   +1 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

TEACHING NARRATIVE WRITING BY USING ROUNDTABLE STRATEGY TO ISLAMIC JUNIOR HIGH SCHOOL STUDENTS

Edukasi: Jurnal Pendidikan dan Pengajaran, 2018
The objectives of this study were to find out whether or not (1) there was a significant improvement on the eighth grade students’ writing achievement between those who were taught by using roundtable strategy, and (2) there was a significant difference ...
Muammar Khadapi
doaj