Results 61 to 70 of about 115,960 (208)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The Effect of A Process Approach Using Report Writing Frame on Students’ Writing Achievement
IJET (Indonesian Journal of English Teaching), 2017 This study is aimed at investigating the effect of process approach using Report Writing Frame on students’ writing achievement. The design of this study was quasi-experimental design.
Khoiriyatul Hariro
doaj +1 more source
Psychophysiological factors as predictors of second language writing achievement in a computer-based test. [PDF]
Front Psychol, 2022 Lee SP, Chang SL, Su HK, Cui ZY, Lee SD.
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Nalans, 2020 The common view that writing skill in a foreign language is difficult to acquire may lead to loss of motivation and therefore lack of success among English as a Foreign Language (EFL) learners.
Recep Şžahin Arslan +1 more
doaj
LLT Journal: A Journal on Language and Language Teaching, 2018 This study aimed at finding out whether or not: (1) there was a significant difference in descriptive writing achievement after they were taught by using process approach through environmental observation and (2) there was a significant difference in ...
Riana Febriyanti +2 more
doaj +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
The effect of web-mediated, blended, and purely online learning on EFL learners' writing achievement in the Iranian context: A comparative study. [PDF]
Educ Inf Technol (Dordr), 2023 Dousti M, Amirian Z.
europepmc +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source