Results 51 to 60 of about 114,157 (262)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

AN ANALYSIS OF STUDENTS WRITING SKILLS: FOCUS ON GRAMMATICAL AND DISCOURSE COMPETENCE

LLT Journal: A Journal on Language and Language Teaching, 2019
This paper presents an analysis of the students writing skills. It is believed that writing is a powerful device to reflect language structure and to promote language learning.
Dini Hadiani
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Multimodal Writing to Promote Global Competence for EFL Learners

Sakarya University Journal of Education, 2020
Multimodal writing refers to a process of writing with a combination of different modes such as visual, auditory, spatial, linguistic and textual. Research shows that multimodal writing has a positive effect on writing skills and learner motivation ...
Sezen Arslan
doaj   +1 more source

Reading, Writing and Political Competence

Polish Sociological Review, 2018
In the present paper we analyze the relation between political competence and media exposure. Taking into account the dynamic transition of media environment related to growing impact of the internet (web 2.0) we made several assumptions about the influence of traditional and new media on political sophistication.
openaire   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Rollenveränderungen bei der studentischen Textproduktion mit KI. Ergebnisse einer bundesweiten Studierendenbefragung

Hermes
Since the release of ChatGPT, generative AI has significantly changed student academic writing and students’ role in the writing process. This article presents the results of a survey conducted in August/September 2023, including 3,997 evaluated ...
Nora Hoffmann, Helena Grünebaum, Sarah Schmidt   +2 more
doaj   +1 more source

IMPROVING STUDENTS’ COMPETENCE IN WRITING DESCRIPTIVE TEXTS THROUGH “FRESH” TECHNIQUE

English Review: Journal of English Education, 2015
: This research was aimed to know whether “FRESH” technique can improve students’ competence in writing descriptive texts. This research was conducted in one of the junior high schools in Banyumas in academic year 2012/2013.
Faisal Aulia, Yasinta Wulandari
doaj   +1 more source