Results 101 to 110 of about 2,349,017 (306)

Kurusu Kuatia (Inscribed Cross): Written Culture and Indigenous Memory in the Reductions of Paraguay (Eighteenth Century)

open access: yesJournal of Early Modern Studies
In the history of the Guaraní reductions, one of the themes that has attracted attention is the indigenous opposition to accepting orders to move after the Treaty of Madrid was signed by the Iberian monarchies in 1750. At this time, there was intense use
Eduardo Santos Neumann
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

INDIAN CULTURAL IMPRINTS IN UZBEKISTAN: WRITTEN HERITAGE

open access: yes, 2022
The subject discussed in this monograph is wide-ranging and important, and it shows the long existing scientific and cultural connections between Central Asia and India through archeological monuments, ancient art and written sources. In the manuscript, the author mentions the Indian cultural imprint in Central Asia, particularly, in Uzbekistan ...
openaire   +1 more source

Reclusion And The Chinese Eremitic Tradition [PDF]

open access: yes, 1993
Aat Vervoorn\u27s Men of the Cliffs and Caves is a groundbreaking study of attitudes held by the scholar-official class concerning the issue of service vis-à-vis reclusion, retirement, and withdrawal.
Berkowitz, Alan
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Stranded People; Mythical Narratives About the First Inhabitants of Mentawai Islands [PDF]

open access: yes, 2012
In this paper, I examine the stories about the origins of the first inhabitants of the Mentawai Islands. My aim is to understand the perspective of the local community in seeing themselves in the particular place and space where they live in the Mentawai
Tulius, J. (Juniator)
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Book review: Sexuality and social justice in Africa: rethinking homophobia and forging resistance [PDF]

open access: yes, 2013
"Sexuality and Social Justice in Africa: Rethinking Homophobia and Forging Resistance." Marc Epprecht. Zed Books. July 2013. --- The persecution of people in Africa on the basis of their homosexual orientation has recently received considerable coverage ...
Lee, Jia Hui
core  

Educational cultural analysis of language assessment rubrics: a case study of Japanese language at a British University [PDF]

open access: yes, 2020
The standard of language assessment is considered to be similar within the same country, but it actually varies from institution to institution even within the UK.
Winch, Junko
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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