Results 111 to 120 of about 442,325 (309)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Visualisation of Written Culture with Digital Collage and Woman Representation: Visualisation of Woman Figure in the Mountain and Sea Themed Turkish Cypriot Legends [PDF]

, 2017
Gürkan Gökaşan, Erdal Aygenç
openalex   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The Importance of Understanding the Meaning of Written English in Japanese Pop Culture : A Survey of Japanese University Students [PDF]

, 2012
Kathryn Zidonis, Robert Dilenschneider
openalex   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Cultura escrita y grupos profesionales: la escritura y la lectura entre los enfermos españoles de los siglos XVI y XVII

Historia. Instituciones. Documentos, 2004
La falta de buenas fuentes estadísticas seriadas hasta el siglo XIX hace que los estudios sobre alfabetización y cultura escrita en España tropiecen con serias dificultades, lo que obliga a la localización y análisis de fuentes de la más diversa ...
Antonio Claret García Martínez
doaj  

The Arabian Nights in Contemporary World Cultures: Global Commodification, Translation, and the Culture Industry, written by Muhsin Al-Musawi [PDF]

, 2023
Moneera Al-Ghadeer
openalex   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Gagauz religious manuscript tradition in the context of Moldavian ethnic and cultural influence (on the example of the origin of the Gagauz version of the Epistle on Sunday)

Revista de Etnologie şi Culturologie, 2017
The religious handwritten tradition of the Gagauzians is investigated in this article. One of the most widespread among Gagauz people is the apocryphal tale of the New Testament – The Epistle About Lord’s Day (“The Epistle of Our Lord Jesus Christ ...
Elizaveta Kvilinkova
doaj  

Music in the Baroque World: History, Culture and, Performance, written by Susan Lewis [PDF]

, 2017
Peter Leech
openalex   +1 more source