Results 141 to 150 of about 5,628,095 (258)

New Zealand deaf adults' perspectives on speech-language therapy for deaf children. [PDF]

J Deaf Stud Deaf Educ
Newbury J, Lamb R, Macrae T.
europepmc   +1 more source

Written Culture of Christian Egypt

, 2018
Opening Lecture and Reception: Written Culture of Christian Egypt To celebrate the opening of the new exhibit Written Culture of Christian Egypt: Coptic Manuscripts from the University of Michigan Collection, we invite you to join us for short lectures ...
Luciana Gabriela Soares Santoprete
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Formalising Question Management Groups: A Critical Constituent of High-Quality Undergraduate Assessment. [PDF]

Clin Teach
Maraj H, Jawaid I.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

The thesis defense as an academic rite: a call for institutional standards of conduct and excellence in postgraduate programs. [PDF]

Acta Cir Bras
Adão D, Pacheco RL, Zanini LYK, Martins GCL, Sacramento MXT, Novais CR, Del Grande LM, Riera R, Linhares MM.   +8 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

An innovative course-based undergraduate research experience (CURE) in HPV-associated cervical cancer: integrating molecular oncology research and scientific writing in undergraduate education. [PDF]

J Microbiol Biol Educ
Baba SK, Baba SK, Jawwad T, Al Menhali A, Mirza S.   +4 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Application of NGS Technology in Osteomyelitis Caused by Human Bites. [PDF]

Infect Drug Resist
Zhao Q, Zou X, Alhaskawi A, Luo M, Li K, Xu J, Lu H.   +6 more
europepmc   +1 more source