Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Victor Jacquemont chez les Taunay : échos d’une polémique dans la presse de Rio de Janeiro, 1839
Brésil(s)The French traveler Victor Jacquemont (1801-1832) made a brief stay in Brazil in 1828, during which he expressed harsh judgments about slavery and the country’s elites in his letters.
Wilma Peres Costa
doaj +1 more source
Irus and his jovial crew : representations of beggars in Vincent Bourne and other eighteenth-century writers of Latin verse [PDF]
, 2013 Alastair Fowler has written, with reference to the time of Milton, of ‘Latin's special role in a bilingual culture’, and this was still true in the early eighteenth century.
Beier +26 more
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
USING PICTURE SERIES TO IMPROVE STUDENTS’ WRITING ABILITY (A Classroom Action Research at the Third Grade Students of MTS NW I Kembang Kerang in the Academic Year of 2010/2011) [PDF]
, 2011 English as the first foreign language in Indonesia is taught starting from the elementary school level up to university level. The general objective of teaching English in Indonesia, based on the school based curriculum (KTSP), is to develop students’
ZAINI, MUHAMMAD
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Problems of culture of written expression in primary school [PDF]
Sinteze, 2014 This paper investigates the issue of the culture of written expression in primary school students. Starting from the fact that teaching practices increasingly points to the fact that knowledge of rules of writing in primary school students presents the ...
Zlatić Marina V. +1 more
doaj +1 more source
A Study of the Film Adaptations of Marek Hłasko's Prose by the Students of the Film School in Łódź [PDF]
, 2012 A Study of the Film Adaptations of Marek Hłasko's Prose by the Students of the Film School in ŁódźThe works of Marek Hłasko have proved a reliable source of content and inspiration in Polish culture from the time of their writing to the current ...
Bucknall-Hołyńska, Justyna
core +2 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source