Results 71 to 80 of about 5,628,095 (258)
HEALTH CARE SPACES: GENERATORS OF WRITTEN CULTURE PRACTICES
This article discusses the written cultural practices carried out by women in a hospital, a pharmacy and their homes, located in a mountainous city a few kilometers away from the city of Cordoba.
Pamela Ayelen Sanchez
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
New Directions in the History of Written Culture
This article reviews some new directions in the history of writing practices, concentrating on Western Europe and the Americas in the nineteenth and early twentieth centuries.
Martyn Lyons
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Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A partir do desenvolvimento urbano e da consolidação das universidades, no século XIII, verifica-se a produção de uma literatura culta com vistas ao diálogo acadêmico e, sobretudo, sob a forma de um projeto educacional para a sociedade cristã.
Ana Paula Tavares Magalhães
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Participant 208 Community Conversations Written
In this written interview, Participant 208 shares about their experience as a college student transitioning from in-person classes to remote learning.
Sabrina
core
Participant 574 Community Conversations Written Interview
In this written interview, Participant 574 shares their experiences during the COVID-19 pandemic, expressing their disappointment that they can no longer meet with friends for a cup of coffee. They express sadness in losing loved ones to COVID-19 and not
Anonymous
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
In the history of the Guaraní reductions, one of the themes that has attracted attention is the indigenous opposition to accepting orders to move after the Treaty of Madrid was signed by the Iberian monarchies in 1750. At this time, there was intense use
Eduardo Santos Neumann
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