Results 271 to 280 of about 382,520 (299)

Proteolytic processing of the X-linked inhibitor of apoptosis protein during Fas-mediated apoptosis.

2009
Apoptosis is a natural cellular function which is tightly controlled along its multiple pathways by positive and negative regulator proteins. Among the negative regulators are the gene family called the IAPs (inhibitor of apoptosis proteins) which were initially identified in baculoviruses.
openaire   +2 more sources

Cisplatin inhibits the expression of X-linked inhibitor of apoptosis protein in human LNCaP cells

Urologic Oncology: Seminars and Original Investigations, 2004
The purpose of the present study is to investigate the role of X-linked inhibitor of apoptosis protein (XIAP) in the regulation of apoptosis induced by cisplatin in human prostate cancer cell line (LNCaP). We examined the effects of cisplatin on cell growth and apoptosis in LNCaP by 2-(4-lodophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H ...
Takeo, Nomura, Hiromitsu, Mimata, Mutsushi, Yamasaki, Yoshio, Nomura   +3 more
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[Expression of X-linked inhibitor of apoptosis protein in colorectal cancer tissues].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2010
To investigate the expression of X-linked inhibitor of apoptosis protein (XIAP) in colorectal cancer tissues and investigate its correlation with the clinicopathological factors of the malignancy.Immunohistochemistry and RT-PCR was employed to detect the expression of XIAP in 87 colorectal cancer tissues.XIAP mRNA expression was detected in 64.4% (56 ...
Bin, Li, Yang-de, Zhang, Bu-ning, Tian
openaire   +1 more source

X-linked inhibitor of apoptosis protein expression and the regulation of apoptosis during human placental development.

Biology of reproduction, 2001
In this study, we have examined the expression and potential role of X-linked inhibitor of apoptosis protein (XIAP), Fas, and Fas ligand (FasL) in the regulation of apoptosis throughout placental development. Protein expression was determined by Western blot analysis and immunohistochemistry, whereas apoptotic cell death was assessed by DNA ...
A, Gruslin, Q, Qiu, B K, Tsang
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Localization of X-Linked Inhibitor of Apoptosis Protein mRNA in Sheep Ovary.

Biology of Reproduction, 2009
Hollian R. Douglas, Ilona C. Kokay, David R. Grattan, Peter R. Hurst   +3 more
openaire   +1 more source

A review of cancer immunotherapy toxicity

Ca-A Cancer Journal for Clinicians, 2020
Lucy Boyce Kennedy
exaly  

10 X-linked inhibitor of apoptosis protein inhibits RIG-I signalling pathway

Cytokine, 2008
Peyman Nakhaei, Thibault Mesplède, Qiang Sun, Simon Leveillé, Robert G. Korneluk, John Hiscott   +5 more
openaire   +1 more source

Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study

Lancet, The, 2013
Marina Cuchel, Dirk J Blom, A David Marais   +2 more
exaly  

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

Cell, 1994
Tony Hunter
exaly  

Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: a randomised phase 2 trial

Lancet, The, 2014
L Kristin Newby, Michael S. Marber, Christian W Hamm   +2 more
exaly