Results 131 to 140 of about 43,167 (288)

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Chromatin Sensing by the Auxiliary Domains of KDM5C Regulates Its Demethylase Activity and Is Disrupted by X-linked Intellectual Disability Mutations. [PDF]

J Mol Biol, 2023
Ugur FS, Kelly MJS, Fujimori DG.
europepmc   +1 more source

Consumer Behavior Toward Health‐Related Mobile Applications: A Hybrid Review and Future Agenda

Journal of Consumer Behaviour, EarlyView.
ABSTRACT Mobile health (MH) has the potential to address many consumer challenges, but consumer responses to it remain varied. In this regard, the consumer's perspective on MH is becoming increasingly attractive to academia and business. This review aims to synthesize and analyze 103 studies from 2010 to 2024 using the Scientific Procedures and ...
Omer Faruk Celebi, Ebru Tumer, Nilsah Cavdar Aksoy, Alev Kocak Alan   +3 more
wiley   +1 more source

Protection or paternalism: A critical evaluation of Australian legislation relating to sexual acts involving persons with intellectual disability

, 2009
As a result of the development and recognition of human rights and of the principle of normalisation, in recent decades sweeping changes have occurred in the living conditions of many people with intellectual disability.
Graydon, Clare Marie
core  

Heterozygous Med13l mice recapitulate a developmental growth delay and craniofacial anomalies seen in MED13L syndrome

Developmental Dynamics, EarlyView.
Abstract Background Gene transcription is crucial for embryo and postnatal development and is regulated by the Mediator complex. Mediator is comprised of four submodules, including the kinase submodule (CKM). The CKM consists of MED13, MED12, CDK8, and CCNC.
Anna K. Leinheiser, Timothy T. Nguyen, Kayla M. Henry, Mariela Rosales, Eric Van Otterloo, Chad E. Grueter   +5 more
wiley   +1 more source

Establishment of a human induced pluripotent stem cell line, KMUGMCi010-A, from a patient with X-linked Ohdo syndrome bearing missense mutation in the MED12 gene

Stem Cell Research
X-linkded Ohdo syndrome is characterized mainly by intellectual disability, delays in reaching development, feeding difficulties, thyroid dysfunction, and dysmorphic appearance with blepharophimosis, immobile mask-like face and bulbous nose. The X-linked
Hiroki Ura, Sumihito Togi, Hisayo Hatanaka, Yo Niida   +3 more
doaj   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

A Novel Mutation in ATRX Causes Alpha-Thalassemia X-Linked Intellectual Disability Syndrome in a Han Chinese Family. [PDF]

Front Pediatr, 2021
Wu S, Zheng Y, Xu C, Fu J, Xiong F, Yang F.   +5 more
europepmc   +1 more source

Rare pathogenic variants in WNK3 cause X-linked intellectual disability

, 2022
Purpose WNK3 kinase (PRKWNK3) has been implicated in the development and function of the brain via its regulation of the cation-chloride cotransporters, but the role of WNK3 in human development is unknown.
EG Seaby (21936320), E Colin (21942890), K Reinson (21942821), A Bouman (16095977), E Ranza (21942806), K Stouffs (21942854), B Cogné (21942779), X Zeng (7533776), H Li (100694), PQ Duy (21942872), M Rio (13704433), SA Coury (21942809), EE Barr (21942827), K Õunap (21942818), FL Raymond (21936344), A Wilson (7726424), SM Berger (21942857), S Mercier (13726816), E Scalais (21942851), T Besnard (21942767), K McWalter (21942803), E Brischoux-Boucher (21942815), F Rajabi (13658326), F Bréhéret (21942845), A Toutain (21942887), MJ Friez (21942893), L Rhodes (12066512), X Blanc (21942812), M van Slegtenhorst (21942839), KG Monaghan (21942833), P Lindenbaum (21942848), S Bézieau (21942905), MH Cobb (21942866), RE Stevenson (21942788), A Caro-Llopis (21942770), X Le Guillou (21942878), S Schmitt (13401132), D Bonneau (15968891), R Redon (20382879), LT Hao (21942785), KT Kahle (21869195), B Gilbert-Dussardier (21942875), SR Akhtar Rizvi (21942899), S Panchagnula (21942869), P Boisseau (21942884), AB Jaykumar (21942863), E Kiziltug (21942773), SE Antonarakis (21942902), JA Rosenfeld (16195511), F Martínez (40334), M Vincent (11863157), WK Chung (14471805), B Isidor (15340268), RJ Louie (21942791), D Grozeva (7655048), EM Pereira (9868541), AJ Kundishora (21942782), CE Schwartz (15891098), S Küry (21859580), Y van Bever (21942836), V Vignard (21942800), S Haider (7925240), SM Robert (21923438), K Retterer (16195505), H Pérez-Peña (21942896), SS Josiah (21925064), SS Milla (21942860), J Zhang (7490018), W Deb (21942794), P Charles (13358310), SH Guihard (21942830), S Odent (13543597), P Ilves (21942824), S Audebert-Bellanger (21942881), A-S Denommé-Pichon (21942776), E Torti (21942797), IM Wentzensen (21319904), D Quinquis (21942842), B Keren (13543861), L Pasquier (16046984)   +79 more
core  

Flexible Direct‐Conversion X‐Ray Detectors: From Emerging Materials to Conformal Imaging

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This comprehensive review analyzed the performance, challenges, and future directions of four emerging material systems for next‐generation flexible direct‐conversion X‐ray detectors: organic semiconductors, perovskites, metal–organic frameworks, and inorganic metal compounds.
Haipeng Di, Guoliang Ma, Jiaxin Mu, Kailian Dong, Haibin Li, Manjing Wang, Xin Song, Haojin Li, Jianwei Xu, Yiying Zhao, Jingjing Zhao, Guojia Fang   +11 more
wiley   +1 more source