Results 141 to 150 of about 8,409,709 (279)

Expert Perspective: Toward Treat‐to‐Target Management in Adult Idiopathic Inflammatory Myopathies

Arthritis &Rheumatology, Accepted Article.
Treat‐to‐target (T2T) has transformed the management of several rheumatic diseases through predefined therapeutic goals, structured disease assessment, and timely treatment adjustment. Despite major advances in the understanding and treatment of idiopathic inflammatory myopathies (IIM), a formal T2T framework for adult IIM has not yet been established.
Shiri Keret, Nantakarn Pongtarakulpanit, Rohit Aggarwal   +2 more
wiley   +1 more source

MDL‐800‐induced SIRT6 activation decreases age‐associated osteoarthritis in mice

Arthritis &Rheumatology, Accepted Article.
Objective SIRT6 is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of a small molecule activator of SIRT6, MDL‐800, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez, Pranay Ramteke, Bahiyah Watson, Owen Haslam, Eirene Choi, Susan Chubinskaya, Mandy J. Peffers, William R. Davis, Jacqueline Shine, Brian O. Diekman, Richard F. Loeser, Theresa A. Freeman, Makarand V. Risbud, John A. Collins   +13 more
wiley   +1 more source

Developing a critical caste analysis within information science and technology: A research review: An Annual Review of Information Science and Technology (ARIST) paper

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Caste—an ascriptive social hierarchy in South Asia and its diaspora—is a globalized phenomenon. Recent caste‐based discrimination, particularly in technology companies and anti‐caste efforts to address it, has compelled academia, policy, and the technology industry to better understand contemporary mechanics of caste.
Nayana Kirasur, Britt Paris
wiley   +1 more source

ALG13 X-linked intellectual disability: New variants, glycosylation analysis, and expanded phenotypes. [PDF]

J Inherit Metab Dis, 2021
Alsharhan H, He M, Edmondson AC, Daniel EJP, Chen J, Donald T, Bakhtiari S, Amor DJ, Jones EA, Vassallo G, Vincent M, Cogné B, Deb W, Werners AH, Jin SC, Bilguvar K, Christodoulou J, Webster RI, Yearwood KR, Ng BG, Freeze HH, Kruer MC, Li D, Raymond KM, Bhoj EJ, Sobering AK.   +25 more
europepmc   +1 more source

Critical questions for documenting collections as data: Provocations from developing datasheets for web archives datasets

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Scholarship on documentation of datasets is increasingly concerned with capturing the context, socio‐technical processes, and decisions shaping data. “Datasheets for datasets” is a recent approach developed by researchers in machine learning that foregrounds transparency and uncovering bias through data documentation.
Emily Maemura, Helena Byrne
wiley   +1 more source

Screening of the duplication 24 pb of ARX gene in Moroccan patients with X-linked Intellectual Disability. [PDF]

BMC Res Notes, 2021
Benmakhlouf Y, Touraine R, Harzallah I, Zian Z, Ben Makhlouf K, Barakat A, Ghailani Nourouti N, Bennani Mechita M.   +7 more
europepmc   +1 more source

The Effect of a Parent Advocacy Intervention on Service Access for Autistic Youth: The Moderating Role of Baseline Advocacy Ability

Autism Research, EarlyView.
ABSTRACT Autistic youth face significant challenges accessing adult disability services as they transition out of school‐based services. Advocating for Supports to Improve Service Transitions (ASSIST), a group‐based program, was developed to address this issue by teaching parents about the service system and how to advocate for services for their youth.
Carly Moser, Leann Smith DaWalt, Meghan M. Burke, Julie Lounds Taylor   +3 more
wiley   +1 more source

Hippocampal Excitatory Synaptic Transmission and Plasticity Are Differentially Altered during Postnatal Development by Loss of the X-Linked Intellectual Disability Protein Oligophrenin-1. [PDF]

Cells, 2022
Cresto N, Lebrun N, Dumont F, Letourneur F, Billuart P, Rouach N.   +5 more
europepmc   +1 more source

Electroconvulsive Therapy for Catatonia in Autistic and Non‐Autistic Patients: An Observational Study on Course, Efficacy, Aggression, and Self‐Injury Outcomes

Autism Research, EarlyView.
ABSTRACT Catatonia occurs disproportionately in autistic individuals and may respond to electroconvulsive therapy (ECT), yet prior reports suggest greater treatment burden in this population. We compared longitudinal ECT utilization, safety, and clinical outcomes between autistic and non‐autistic patients with catatonia.
Joshua Ryan Smith, Maria Bonnee, Sarah Marler, Seri Lim, D. Catherine Fuchs, Rafael Tamargo, Isaac Baldwin, Christopher Maley, Ashley VanHaverbeck, Courtney Hamilton, Timothy Adegoke, Haozheng Xu, Jinyuan Liu, Zachary J. Williams, Jo Ellen Wilson, James Luccarelli   +15 more
wiley   +1 more source

X-linked intellectual disability with marfanoid habitus [PDF]

, 2020
openaire   +1 more source