Results 81 to 90 of about 2,319,252 (294)
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
Chandra-SDSS Normal and Star-Forming Galaxies I: X-ray Source Properties of Galaxies Detected by Chandra in SDSS DR2 [PDF]
We have cross-correlated X-ray catalogs derived from archival Chandra ACIS observations with a Sloan Digital Sky Survey (SDSS) Data Release 2 (DR2) galaxy catalog to form a sample of 42 serendipitously X-ray detected galaxies over the redshift interval 0.03 < z < 0.25.
arxiv +1 more source
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé+7 more
wiley +1 more source
The viral nature of many female genital cancers is now beyond question. By taking into account this fact, the problem of qualitative assessment ofthenatureofcervicalintraepithelialneoplasia(CIN)anditsfocusonprogressiontoinvasivecarcinomabecomesquitenatu ...
V. K. Bozhenko+9 more
doaj +1 more source
Background The main method for preventing thrombotic complications in patients with coronavirus infection is anticoagulant therapy (ACT). However, its use is not always possible, in particular in patients with bleeding.
R. E. Kalinin+5 more
doaj +1 more source
X-ray source population study of the starburst galaxy M83 with XMM-Newton [PDF]
We present the results obtained from the analysis of three XMM-Newton observations of M83. The aims of the paper are studying the X-ray source populations in M83 and calculating the X-ray luminosity functions of X-ray binaries for different regions of the galaxy. We detected 189 sources in the XMM-Newton field of view in the energy range of 0.2-12 keV.
arxiv +1 more source
X-ray Polarimetry of X-ray Pulsars
Radiation from X-ray pulsars (XRPs) was expected to be strongly linearly polarized owing to a large difference in their ordinary and extraordinary mode opacities. The launch of IXPE allowed us to check this prediction. IXPE observed a dozen X-ray pulsars, discovering pulse-phase dependent variation of the polarization degree (PD) and polarization angle
Juri Poutanen+2 more
openaire +3 more sources
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
The channel structure of trithallium pentaantimonate(V), Tl3Sb5O14
Single crystals of Tl3Sb5O14 were grown by solid-state reaction in a corundum crucible under air (1273 K, 12 h). The structure was determined by single-crystal X-ray diffraction.
Paul Sicher, Berthold Stöger
doaj +1 more source