Visualization of Mobile Regions in Proteins by X-Ray Crystallography.
Hiroaki Kato, Jun’ichi Oda
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Low Symmetry Cage Complexes Formed by Metalation of Symmetric Hexa‐Cationic Organic Cages
Threefold symmetric hexa‐cationic hydrazone cages coordinate a range of transition metal ions upon deprotonation. When the cage contains ethyl solubilising groups the expected threefold symmetric cage complexes are observed, however when the cage contains alkoxy solubilising groups persistent low symmetry cage complexes form.
Rosemary J. Goodwin+2 more
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Cyclic Olefin Copolymer-Based Fixed-Target Sample Delivery Device for Protein X-ray Crystallography. [PDF]
Manna A+15 more
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Discrete Actuation of Water‐Responsive Crystalline Metal–Peptide Frameworks
We design metal–peptide frameworks that exhibit either continuous or discrete threshold water‐responsive actuation by tuning water‐binding affinities and structural dynamics. In the continuous actuation mode, water molecules evaporate sequentially due to varying interaction strengths and structural roles.
Hui Yuan+12 more
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Synergism between x-ray crystallography and NMR residual dipolar couplings in characterizing protein dynamics. [PDF]
Shen Y, Bax A.
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Potent Fluorescent Probe for Target‐Engagement Studies of Allosteric Pyruvate Kinase Modulators
LumiPK, a novel environment‐sensitive fluorescent tracer, enables direct monitoring of allosteric ligand engagement with pyruvate kinase fused with nanoluciferase (Nluc), focusing on the liver isoform (PKL). In NanoBRET, and fluorescence indicator displacement assays, LumiPK shows high affinity and validates known allosteric modulators of PKL.
Oscar Nilsson+9 more
wiley +2 more sources
AnACor2.0: a GPU-accelerated open-source software package for analytical absorption corrections in X-ray crystallography. [PDF]
Lu Y+5 more
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Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro, and X-ray Crystallography. [PDF]
Yoshino R+13 more
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Principles of protein X-ray crystallographyby J. Drenth [PDF]
S. E. Ealick
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