Results 61 to 70 of about 1,291,187 (318)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
, 2012 The complex architecture of their structural elements and compartments is a hallmark of eukaryotic cells. The creation of high resolution models of whole cells has been limited by the relatively low resolution of conventional light microscopes and the ...
Achilleas S. Frangakis +32 more
core +1 more source
, 2022 X‐rays are emerging as a complementary probe to visible‐light photons and electrons for imaging biological cells. By exploiting their small wavelength and high penetration depth, it is possible to image whole, intact cells and resolve subcellular ...
Cassini, Chiara +14 more
core +1 more source
Advanced Materials InterfacesWith advancements in the semiconductor industry, the complexity of three‐dimensional (3D) nanostructures becomes higher with continuously decreasing feature sizes.
Vinh‐Binh Truong +4 more
doaj +1 more source
Advanced Non-Destructive Ocular Visualization Methods by Improved X-Ray Imaging Techniques. [PDF]
PLoS ONE, 2017 Due to limited X-ray contrast, the use of micro-CT in histology is so far not as widespread as predicted. While specific staining procedures-mostly using iodine-address this shortcoming, long diffusion times restrict its use in the often time-constrained
Christian Enders +9 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Combined control of aluminum bath composition by X‐ray diffraction and X‐ray fluorescence analysis
, 2020 Текст статьи не публикуется в открытом доступе в соответствии с политикой журнала.The present paper provides a combined application of X‐ray diffraction (XRD) and X‐ray fluorescence (XRF) methods in process control for the analysis of aluminum baths of ...
Alexandr, Samoilo +9 more
core +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Double-sided fresnel zone plates as high performance optics in X-ray microscopy [PDF]
, 2015 X-ray microscopy describes a range of analytical techniques, specialized for the characterization of organic and inorganic samples using high energy photons.
Mohácsi, István
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source