Results 61 to 70 of about 1,203,775 (345)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
DISCRETE X-RAY SOURCES IN GALAXY CLUSTERS
Odessa Astronomical Publications, 2020 Current studies of extragalactic X-ray sources using data from orbital observatory XMM- Newton are at the front line of X-ray astronomy. Resolution capacity of the observatory instruments enable to detect separate X-ray sources in the close galaxies.
A. V. Tugay +2 more
doaj +1 more source
Four-type phase-contrast X-ray imaging at SAGA Light Source [PDF]
, 2022 Akio Yoneyama +3 more
openalex +1 more source
Hard Cosmic X-ray Sources [PDF]
Symposium - International Astronomical Union, 1973 A review of the observational status of X-ray sources detected in the 20 ⋍ 500 keV range is presented. Of the approximately 115 sources listed in the March 1972 edition of the UHURU 2–6 keV sky survey catalog, about 15 sources have been studied in hard X-rays.
openaire +1 more source
X-ray background and its correlation with the 21 cm signal [PDF]
, 2018 We use high resolution hydrodynamical simulations to study the contribution to the X-ray background from high-$z$ energetic sources, such as X-ray binaries, accreting nuclear black holes and shock heated interstellar medium.
Ciardi, B. +3 more
core +2 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Periods in X-Ray Sources [PDF]
Highlights of Astronomy, 1977 Known periodicities in X-ray sources cover a wide range of values - a factor of 108or 109from the 33 mS of the Crab pulsar up to 35 days for the Her X-1 repeat of its up state, or even years if one believes in the not inconceivable idea that at least one “transient” (perhaps not yet even discovered!) is exhibiting some form of repetitive behaviour ...
openaire +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
The Astrophysical Journal, 2023 Gamma-ray binary systems, a subclass of high-mass X-ray binaries, show nonthermal emissions from radio to TeV. While efficient electron acceleration is considered to take place in them, the nature of the acceleration mechanism and the physical ...
Hiroki Yoneda +7 more
doaj +1 more source
Long-term X-ray variability of ultraluminous X-ray sources [PDF]
Monthly Notices of the Royal Astronomical Society, 2015 15 pages, 8 figures; accepted for publication in ...
Hu, CP +5 more
openaire +4 more sources