Results 81 to 90 of about 1,327,251 (363)
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
X-Ray Polarimetry of the Accreting Pulsar 1A 0535+262 in the Supercritical State with PolarLight
The X-ray pulsar 1A 0535+262 exhibited a giant outburst in 2020, offering us a unique opportunity for X-ray polarimetry of an accreting pulsar in the supercritical state.
Xiangyun Long+27 more
doaj +1 more source
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
Creep Characterization of Inconel 718 Lattice Metamaterials Manufactured by Laser Powder Bed Fusion
Herein, the creep characteristics of additively manufactured Inconel 718 metamaterials are investigated. The creep behavior of metamaterials and the effects of microstructural defects are assessed, and the microstructure defects are accurately captured using Kachanov's creep damage model.
Akash Singh Bhuwal+5 more
wiley +1 more source
We present a detailed compilation and analysis of the X-ray phase space of low- to intermediate-redshift (0 ≤ z ≤ 1) transients that consolidates observed light curves (and theory where necessary) for a large variety of classes of transient/variable ...
Ava Polzin+10 more
doaj +1 more source
An XMM-Newton View of the ANdromeda Galaxy as Explored in a Legacy Survey (New-ANGELS) I: the X-ray Source Catalogue [PDF]
We introduce the New-ANGELS program, an XMM-Newton survey of $\sim7.2\rm~deg^2$ area around M 31, which aims to study the X-ray populations in M 31 disk and the X-ray emitting hot gas in the inner halo of M 31 up to 30 kpc. In this first paper, we report the catalogue of 4506 detected X-ray sources, and attempt to cross-identify or roughly classify ...
arxiv
Displacement of X-Ray Sources from Star Clusters in Starburst Galaxies [PDF]
We examine the spatial offsets between X-ray point sources and star clusters in three starburst galaxies. We find that the X-ray sources are preferentially located near the star clusters. Because the star clusters are very good tracers of the star formation activity in the galaxies, this indicates that the X-ray sources are young objects associated ...
arxiv +1 more source
Mapping Hsp104 interactions using cross‐linking mass spectrometry
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal+3 more
wiley +1 more source
A Variational Beam Model for Failure of Cellular and Truss‐Based Architected Materials
Herein, a versatile and efficient beam modeling framework is developed to predict the nonlinear response and failure of cellular, truss‐based, and woven architected materials. It enables the exploration of their design space and the optimization of their mechanical behavior in the nonlinear regime. A variational formulation of a beam model is presented
Konstantinos Karapiperis+3 more
wiley +1 more source
We present the results of X-ray and Near-Infrared observations of the Galactic Ridge X-ray Emission (GRXE). We extracted 2,002 X-ray point sources in the Chandra Bulge Field (l =0°.113, b = 1°.424) down to ~10-14.8 ergscm-2s-1 in 2-8 keV band with the ...
Kumiko Morihana+2 more
doaj +1 more source