Results 81 to 90 of about 7,431,143 (302)
The high-redshift Universe with the International X-ray Observatory
, 2011 We discuss some of the main open issues related to the light-up and evolution of the first accreting sources powering high redshift luminous quasars. We discuss the perspectives of future deep X-ray surveys with the International X-ray Observatory and ...
RANALLI, PIERO +5 more
core
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Formation of dark matter halos is sensitive to the expansion rate of the Universe and to the growth of structures under gravitational collapse. Virialization of halos heats the gaseous intra-cluster medium to high temperatures, leading to copious ...
Finoguenov, Alexis, Clerc, Nicolas
core +1 more source
The Astrophysical JournalWe present a framework to crossmatch sources from the Chandra Source Catalog (CSC v2.1) with optical sources from Gaia Data Release 3. Unlike purely spatial approaches, we use source properties such as magnitudes, colors, and distances to identify true ...
V. Samuel Pérez-Díaz +8 more
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
The Astrophysical Journal Supplement SeriesWe present a catalog of hard X-ray serendipitous sources detected in the first 80 months of observations by the Nuclear Spectroscopic Telescope Array (NuSTAR).
Claire L. Greenwell +34 more
doaj +1 more source
Astronomy & AstrophysicsContext. The integrated X-ray luminosity (LX) of star-forming galaxies originates primarily from populations of high-mass X-ray binaries (HMXBs). However, the discrete nature of these populations introduces stochastic sampling effects, affecting the ...
Kyritsis E., Zezas A., Kovlakas K.
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
TeV gamma-ray emission from accreting binary pulsars [PDF]
, 1990 The high-mass X-ray binary SMC X-1 has been observed during the interval 1986-1989 at a threshold γ-ray energy of 0.4 TeV using the University of Durham Mark III air Cerenkov telescope at Narrabri.
Mannings, Vincent, Mannings, V
core
High-z X-ray obscured quasars in galaxies with extreme mid-IR/optical colors
, 2009 Extreme Optical/Mid-IR color cuts have been used to uncover a population of dustenshrouded, mid-IR luminous galaxies at high redshifts. Several lines of evidence point towards the presence of an heavily absorbed, possibly Compton-thick quasar at ...
Feruglio C. +6 more
core +1 more source