Results 81 to 90 of about 67,039 (310)

ESA INTEGRAL and Cataclysmic Variables

Odessa Astronomical Publications, 2017
The satellite INTEGRAL is ESA project operating since January 2003. It is dedicated to high energy astronomy. INTEGRAL is able to detect and perform astrometry, photometry and spectroscopy of sources from X-ray to gamma-ray regime (nominal range of ...
Jan Strobl, René Hudec, Vojtéch Simon, Filip Hroch, INTEGRAL CP CVs Working Group   +4 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

The high-redshift Universe with the International X-ray Observatory

, 2011
We discuss some of the main open issues related to the light-up and evolution of the first accreting sources powering high redshift luminous quasars. We discuss the perspectives of future deep X-ray surveys with the International X-ray Observatory and ...
RANALLI, PIERO, VIGNALI, CRISTIAN, Comastri A., Gilli R., BRUSA, MARCELLA, Civano F.   +5 more
core  

The NuSTAR Serendipitous Survey: The 80 Month Catalog and Source Properties of the High-energy Emitting Active Galactic Nucleus and Quasar Population

The Astrophysical Journal Supplement Series
We present a catalog of hard X-ray serendipitous sources detected in the first 80 months of observations by the Nuclear Spectroscopic Telescope Array (NuSTAR).
Claire L. Greenwell, Lizelke Klindt, George B. Lansbury, David J. Rosario, David M. Alexander, James Aird, Daniel Stern, Karl Forster, Michael J. Koss, Franz E. Bauer, Claudio Ricci, John Tomsick, William N. Brandt, Thomas Connor, Peter G. Boorman, Adlyka Annuar, David R. Ballantyne, Chien-Ting Chen, Francesca Civano, Andrea Comastri, Victoria A. Fawcett, Francesca M. Fornasini, Poshak Gandhi, Fiona Harrison, Marianne Heida, Ryan Hickox, Elias S. Kammoun, Lauranne Lanz, Stefano Marchesi, Gaël Noirot, Encarni Romero-Colmenero, Ezequiel Treister, C. Megan Urry, Petri Väisänen, Brian van Soelen   +34 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

BASS. XLV. Quantifying Active Galactic Nuclei Selection Effects in the Chandra COSMOS-legacy Survey with BASS

The Astrophysical Journal
Deep extragalactic X-ray surveys, such as the Chandra COSMOS-Legacy field (CCLS), are prone to be biased against active galactic nuclei (AGN) with high column densities due to their lower count rates at a given luminosity.
Yarone M. Tokayer, Michael J. Koss, C. Megan Urry, Priyamvada Natarajan, Richard Mushotzky, Mislav Baloković, Franz E. Bauer, Peter Boorman, Alessandro Peca, Claudio Ricci, Federica Ricci, Daniel Stern, Ezequiel Treister, Benny Trakhtenbrot   +13 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

The BMW Deep X-Ray Cluster Survey [PDF]

, 2006
3 pages, 2 figures; to appear in Proc. of the ESO/ECF/STSCI workshop on "Deep Fields", Garching Oct 2000, (Publ: Springer)
Guzzo, L., Moretti, A., Campana, S., Covino, S., Dell'Antonio, I., Lazzati, D., Longhetti, M., Molinari, E., Panzera, M. R., Tagliaferri, G.   +9 more
openaire   +2 more sources