Results 71 to 80 of about 67,039 (310)
Simulating the Sensitivity to Stellar Point Sources of Chandra X-Ray Observations
, 2023 The Chandra Cygnus OB2 Legacy Survey is a wide and deep X-ray survey of the nearby and massive Cygnus OB2 association. The survey has detected ∼8000 X-ray sources, the majority of which are pre-main-sequence X-ray-emitting young stars in the association ...
Vinay L. Kashyap +10 more
core +1 more source
The Astrophysical Journal, 2023 We present X-ray spectral analysis of XMM-Newton and Chandra observations in the 31.3 deg ^2 Stripe-82X (S82X) field. Of the 6181 unique X-ray sources in this field, we analyze a sample of 2937 candidate active galactic nuclei (AGNs) with solid redshifts
Alessandro Peca +13 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Very High Energy Gamma-Rays from Binary Systems [PDF]
, 2010 This thesis presents a study of the very high energy (VHE) gamma-ray emission from X-ray binary systems using the H.E.S.S. imaging atmospheric Cherenkov array.
DICKINSON, HUGH,JOHN +1 more
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
The Astrophysical JournalWe present the second NuSTAR and XMM-Newton extragalactic survey of the JWST north ecliptic pole (NEP) time-domain field (TDF). The first NuSTAR NEP-TDF survey had 681 ks total exposure time executed in NuSTAR cycle 5 in 2019 and 2020. This second survey,
Xiurui Zhao +32 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The Wide Field X-ray Telescope
, 2009 The Wide Field X-Ray Telescope (WFXT) is a medium-class mission designed to be 2-orders-of-magnitude more sensitive than any previous or planned X-ray mission for large area surveys and to match in sensitivity the next generation of wide-area optical, IR
PAOLILLO, MAURIZIO
core
STROBE-X: X-ray Timing and Spectroscopy on Dynamical Timescales from Microseconds to Years [PDF]
, 2019 We present the Spectroscopic Time-Resolving Observatory for Broadband Energy X-rays (STROBE-X), a probe-class mission concept selected for study by NASA. It combines huge collecting area, high throughput, broad energy coverage, and excellent spectral and
Zane, S, STROBE X team, Ray, P
core
The Wide Field X-ray Telescope Mission-A Digital Sky Survey in X-rays
, 2010 Sensitive surveys of the X-ray universe have been limited to small areas of the sky due to the intrinsically small field of view of Wolter-1 X-ray optics. High angular resolution is needed to achieve a low background per source, minimize source confusion,
M. Paolillo +21 more
core +1 more source